Multicentric Castleman's disease associated with inherited epidermolysis bullosa

Yoshio Kawakami, Akiko Nishibu, Satoshi Kikuchi, Mikio Ohtsuka, Koichiro Nakamura, Yoshihiro Nozawa, Masafumi Abe, Keiji Iwatsuki, Fumio Kaneko

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Multicentric Castleman's disease (MCD) is a rare disorder characterized by fever, polyclonal hypergammaglobulinemia, and generalized lymphadenopathy. It has three histological characteristics: a recognizable architecture, germinal center abnormalities, and plasmacytosis. Inherited epidermolysis bullosa (EB) is also a rare disorder caused by a genetic defect. We report a 43-year-old patient with dystrophic EB, non-Hallopeau-Siemens recessive type or dominant type, displaying clinicopathologic features of MCD. In addition, his serum interleukin-6, which is thought to be responsible for the clinical symptoms in MCD, was elevated.

Original languageEnglish
Pages (from-to)689-693
Number of pages5
JournalJournal of Dermatology
Volume30
Issue number9
Publication statusPublished - Sep 1 2003

Fingerprint

Epidermolysis Bullosa
Epidermolysis Bullosa Dystrophica
Hypergammaglobulinemia
Germinal Center
Interleukin-6
Fever
Serum
Multi-centric Castleman's Disease

Keywords

  • Dystrophic epidermolysis bullosa
  • Hypergammaglobulinemia
  • Interleukin-6

ASJC Scopus subject areas

  • Dermatology

Cite this

Kawakami, Y., Nishibu, A., Kikuchi, S., Ohtsuka, M., Nakamura, K., Nozawa, Y., ... Kaneko, F. (2003). Multicentric Castleman's disease associated with inherited epidermolysis bullosa. Journal of Dermatology, 30(9), 689-693.

Multicentric Castleman's disease associated with inherited epidermolysis bullosa. / Kawakami, Yoshio; Nishibu, Akiko; Kikuchi, Satoshi; Ohtsuka, Mikio; Nakamura, Koichiro; Nozawa, Yoshihiro; Abe, Masafumi; Iwatsuki, Keiji; Kaneko, Fumio.

In: Journal of Dermatology, Vol. 30, No. 9, 01.09.2003, p. 689-693.

Research output: Contribution to journalArticle

Kawakami, Y, Nishibu, A, Kikuchi, S, Ohtsuka, M, Nakamura, K, Nozawa, Y, Abe, M, Iwatsuki, K & Kaneko, F 2003, 'Multicentric Castleman's disease associated with inherited epidermolysis bullosa', Journal of Dermatology, vol. 30, no. 9, pp. 689-693.
Kawakami Y, Nishibu A, Kikuchi S, Ohtsuka M, Nakamura K, Nozawa Y et al. Multicentric Castleman's disease associated with inherited epidermolysis bullosa. Journal of Dermatology. 2003 Sep 1;30(9):689-693.
Kawakami, Yoshio ; Nishibu, Akiko ; Kikuchi, Satoshi ; Ohtsuka, Mikio ; Nakamura, Koichiro ; Nozawa, Yoshihiro ; Abe, Masafumi ; Iwatsuki, Keiji ; Kaneko, Fumio. / Multicentric Castleman's disease associated with inherited epidermolysis bullosa. In: Journal of Dermatology. 2003 ; Vol. 30, No. 9. pp. 689-693.
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