Morphological transformation of sensory ganglion neurons and satellite cells

Seiji Matsuda, Naoto Kobayashi, Katsumi Mominoki, Hiroyuki Wakisaka, Masahiko Mori, Shingo Murakami

Research output: Contribution to journalArticle

Abstract

Sensory ganglion neurons in higher vertebrates are unique in that they are pseudounipolar with a single stem process that divides at some distance from the cell body into central and peripheral processes. In the early stages of development, these neurons are bipolar but later they became pseudounipolar. This developmental process of sensory ganglion neurons with satellite cells was examined by scanning electron microscopy following removal of connective tissue. This pseudo-unipolarization began earlier but proceeded at a slower rate in chick than in rat embryos. This difference may due to the difference found in the extent and intimacy of satellite cell investments in these two animals, which was due to the fact that sensory neurons undergo pseudo-unipolarization only in the presence of satellite cells in vitro. The neuronal perikaryal projections were observed by scanning electron microscopy after removal of connective tissue and satellite cells. Morphometric analysis reveal that perikaryal projections were more numerous on the surface of mature pseudounipolar neurons than on the surface of premature bipolar neurons, and that the number of projections increased as the neuronal cell bodies grew larger. This may support the hypothesis that perikaryal projections are structural devices for increasing the neuron-satellite interface and for improving the efficiency of metabolic exchange between these two cell types. These results suggest that satellite cells play an important role in neuronal maturation.

Original languageEnglish
Pages (from-to)603-613
Number of pages11
JournalActa Anatomica Nipponica
Volume73
Issue number6
Publication statusPublished - Dec 1998
Externally publishedYes

Fingerprint

Sensory Ganglia
Sensory Receptor Cells
Neurons
Electron Scanning Microscopy
Connective Tissue Cells
Connective Tissue
Vertebrates
Embryonic Structures
Equipment and Supplies

Keywords

  • Metabolic exchange of neurons
  • Perikaryal projection
  • Pseudo-unipolarization
  • Scanning electron microscopy
  • Sensory neuron

ASJC Scopus subject areas

  • Anatomy

Cite this

Matsuda, S., Kobayashi, N., Mominoki, K., Wakisaka, H., Mori, M., & Murakami, S. (1998). Morphological transformation of sensory ganglion neurons and satellite cells. Acta Anatomica Nipponica, 73(6), 603-613.

Morphological transformation of sensory ganglion neurons and satellite cells. / Matsuda, Seiji; Kobayashi, Naoto; Mominoki, Katsumi; Wakisaka, Hiroyuki; Mori, Masahiko; Murakami, Shingo.

In: Acta Anatomica Nipponica, Vol. 73, No. 6, 12.1998, p. 603-613.

Research output: Contribution to journalArticle

Matsuda, S, Kobayashi, N, Mominoki, K, Wakisaka, H, Mori, M & Murakami, S 1998, 'Morphological transformation of sensory ganglion neurons and satellite cells', Acta Anatomica Nipponica, vol. 73, no. 6, pp. 603-613.
Matsuda S, Kobayashi N, Mominoki K, Wakisaka H, Mori M, Murakami S. Morphological transformation of sensory ganglion neurons and satellite cells. Acta Anatomica Nipponica. 1998 Dec;73(6):603-613.
Matsuda, Seiji ; Kobayashi, Naoto ; Mominoki, Katsumi ; Wakisaka, Hiroyuki ; Mori, Masahiko ; Murakami, Shingo. / Morphological transformation of sensory ganglion neurons and satellite cells. In: Acta Anatomica Nipponica. 1998 ; Vol. 73, No. 6. pp. 603-613.
@article{5085b0910edb49aca32844fe0e04ab35,
title = "Morphological transformation of sensory ganglion neurons and satellite cells",
abstract = "Sensory ganglion neurons in higher vertebrates are unique in that they are pseudounipolar with a single stem process that divides at some distance from the cell body into central and peripheral processes. In the early stages of development, these neurons are bipolar but later they became pseudounipolar. This developmental process of sensory ganglion neurons with satellite cells was examined by scanning electron microscopy following removal of connective tissue. This pseudo-unipolarization began earlier but proceeded at a slower rate in chick than in rat embryos. This difference may due to the difference found in the extent and intimacy of satellite cell investments in these two animals, which was due to the fact that sensory neurons undergo pseudo-unipolarization only in the presence of satellite cells in vitro. The neuronal perikaryal projections were observed by scanning electron microscopy after removal of connective tissue and satellite cells. Morphometric analysis reveal that perikaryal projections were more numerous on the surface of mature pseudounipolar neurons than on the surface of premature bipolar neurons, and that the number of projections increased as the neuronal cell bodies grew larger. This may support the hypothesis that perikaryal projections are structural devices for increasing the neuron-satellite interface and for improving the efficiency of metabolic exchange between these two cell types. These results suggest that satellite cells play an important role in neuronal maturation.",
keywords = "Metabolic exchange of neurons, Perikaryal projection, Pseudo-unipolarization, Scanning electron microscopy, Sensory neuron",
author = "Seiji Matsuda and Naoto Kobayashi and Katsumi Mominoki and Hiroyuki Wakisaka and Masahiko Mori and Shingo Murakami",
year = "1998",
month = "12",
language = "English",
volume = "73",
pages = "603--613",
journal = "Kaibogaku zasshi. Journal of anatomy",
issn = "0022-7722",
publisher = "Wiley-Blackwell",
number = "6",

}

TY - JOUR

T1 - Morphological transformation of sensory ganglion neurons and satellite cells

AU - Matsuda, Seiji

AU - Kobayashi, Naoto

AU - Mominoki, Katsumi

AU - Wakisaka, Hiroyuki

AU - Mori, Masahiko

AU - Murakami, Shingo

PY - 1998/12

Y1 - 1998/12

N2 - Sensory ganglion neurons in higher vertebrates are unique in that they are pseudounipolar with a single stem process that divides at some distance from the cell body into central and peripheral processes. In the early stages of development, these neurons are bipolar but later they became pseudounipolar. This developmental process of sensory ganglion neurons with satellite cells was examined by scanning electron microscopy following removal of connective tissue. This pseudo-unipolarization began earlier but proceeded at a slower rate in chick than in rat embryos. This difference may due to the difference found in the extent and intimacy of satellite cell investments in these two animals, which was due to the fact that sensory neurons undergo pseudo-unipolarization only in the presence of satellite cells in vitro. The neuronal perikaryal projections were observed by scanning electron microscopy after removal of connective tissue and satellite cells. Morphometric analysis reveal that perikaryal projections were more numerous on the surface of mature pseudounipolar neurons than on the surface of premature bipolar neurons, and that the number of projections increased as the neuronal cell bodies grew larger. This may support the hypothesis that perikaryal projections are structural devices for increasing the neuron-satellite interface and for improving the efficiency of metabolic exchange between these two cell types. These results suggest that satellite cells play an important role in neuronal maturation.

AB - Sensory ganglion neurons in higher vertebrates are unique in that they are pseudounipolar with a single stem process that divides at some distance from the cell body into central and peripheral processes. In the early stages of development, these neurons are bipolar but later they became pseudounipolar. This developmental process of sensory ganglion neurons with satellite cells was examined by scanning electron microscopy following removal of connective tissue. This pseudo-unipolarization began earlier but proceeded at a slower rate in chick than in rat embryos. This difference may due to the difference found in the extent and intimacy of satellite cell investments in these two animals, which was due to the fact that sensory neurons undergo pseudo-unipolarization only in the presence of satellite cells in vitro. The neuronal perikaryal projections were observed by scanning electron microscopy after removal of connective tissue and satellite cells. Morphometric analysis reveal that perikaryal projections were more numerous on the surface of mature pseudounipolar neurons than on the surface of premature bipolar neurons, and that the number of projections increased as the neuronal cell bodies grew larger. This may support the hypothesis that perikaryal projections are structural devices for increasing the neuron-satellite interface and for improving the efficiency of metabolic exchange between these two cell types. These results suggest that satellite cells play an important role in neuronal maturation.

KW - Metabolic exchange of neurons

KW - Perikaryal projection

KW - Pseudo-unipolarization

KW - Scanning electron microscopy

KW - Sensory neuron

UR - http://www.scopus.com/inward/record.url?scp=0032242328&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0032242328&partnerID=8YFLogxK

M3 - Article

C2 - 9990197

AN - SCOPUS:33747072602

VL - 73

SP - 603

EP - 613

JO - Kaibogaku zasshi. Journal of anatomy

JF - Kaibogaku zasshi. Journal of anatomy

SN - 0022-7722

IS - 6

ER -