Molecular cloning and sequence analysis of the chick melanocortin 1-receptor gene

Sakae Takeuchi, Hideyuki Suzuki, Sayoko Hirose, Masafumi Yabuuchi, Chikara Sato, Hiroaki Yamamoto, Sumio Takahashi

Research output: Contribution to journalArticle

60 Citations (Scopus)

Abstract

The chick melanocortin 1-receptor gene was isolated. It is found to be an intronless gene encoding a 314 amino acid protein, sharing 64% identity with mammalian counterparts. A cis-element responsible for melanocyte-specific transcription is found in its 5' upstream region. It is probable that the expression of the receptor in melanocytes is closely correlated with that of melanogenesis-related genes.

Original languageEnglish
Pages (from-to)122-126
Number of pages5
JournalBiochimica et Biophysica Acta - Gene Structure and Expression
Volume1306
Issue number2-3
DOIs
Publication statusPublished - May 2 1996

Keywords

  • chicken
  • genomic DNA sequencing
  • melanocortin 1-receptor

ASJC Scopus subject areas

  • Structural Biology
  • Biophysics
  • Biochemistry
  • Genetics

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