The chick melanocortin 1-receptor gene was isolated. It is found to be an intronless gene encoding a 314 amino acid protein, sharing 64% identity with mammalian counterparts. A cis-element responsible for melanocyte-specific transcription is found in its 5' upstream region. It is probable that the expression of the receptor in melanocytes is closely correlated with that of melanogenesis-related genes.
|Number of pages||5|
|Journal||Biochimica et Biophysica Acta - Gene Structure and Expression|
|Publication status||Published - May 2 1996|
- genomic DNA sequencing
- melanocortin 1-receptor
ASJC Scopus subject areas
- Structural Biology