Abstract
Objective: To evaluate the diagnostic value of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) for minor salivary gland tumors in the oral cavity. Materials and methods: Thirty-two patients with minor salivary gland tumors were examined preoperatively using DCE-MRI. Their maximum contrast index (CImax), time of CImax (Tmax), Tpeak; i.e., the time that corresponded to the CImax × 0.90, and washout ratios (WR300 and WR600) were determined from contrast index (CI) curves. We compared these parameters between benign and malignant tumors and among the different histopathological types of minor salivary gland tumors. Then, we categorized the patients' CI curves into four patterns (gradual increase, rapid increase with high washout ratio, rapid increase with low washout, and flat). Results: Statistically significant differences in Tmax (P = 0.004) and Tpeak (P = 0.002) were observed between the benign and malignant tumors. Regarding each histopathological tumor type, significant differences in Tmax (P <0.001), Tpeak (P <0.001), and WR600 (P = 0.026) were observed between the pleomorphic adenomas and mucoepidermoid carcinomas. It was difficult to distinguish between benign and malignant tumors using our CI curve classification because that two-thirds of the cases were classified into the same type (gradual increase). Conclusion: The DCE-MRI parameters of minor salivary gland tumors contributed little to their differential diagnosis compared with those for major salivary gland tumors. During the diagnosis of minor salivary gland tumors, Tmax is useful for distinguishing between benign and malignant tumors.
| Original language | English |
|---|---|
| Pages (from-to) | 2684-2691 |
| Number of pages | 8 |
| Journal | European Journal of Radiology |
| Volume | 81 |
| Issue number | 10 |
| DOIs | |
| Publication status | Published - Oct 2012 |
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Keywords
- Adenoid cystic carcinoma
- Dynamic MRI
- Minor salivary gland tumor
- MRI
- Mucoepidermoid carcinoma
- Oral
- Pleomorphic adenoma
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging
Cite this
Minor salivary gland tumors in the oral cavity : Diagnostic value of dynamic contrast-enhanced MRI. / Matsuzaki, Hidenobu; Yanagi, Yoshinobu; Hara, Marina; Katase, Naoki; Asaumi, Jun-Ichi; Hisatomi, Miki; Unetsubo, Teruhisa; Konouchi, Hironobu; Takenobu, Toshihiko; Nagatsuka, Hitoshi.
In: European Journal of Radiology, Vol. 81, No. 10, 10.2012, p. 2684-2691.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Minor salivary gland tumors in the oral cavity
T2 - Diagnostic value of dynamic contrast-enhanced MRI
AU - Matsuzaki, Hidenobu
AU - Yanagi, Yoshinobu
AU - Hara, Marina
AU - Katase, Naoki
AU - Asaumi, Jun-Ichi
AU - Hisatomi, Miki
AU - Unetsubo, Teruhisa
AU - Konouchi, Hironobu
AU - Takenobu, Toshihiko
AU - Nagatsuka, Hitoshi
PY - 2012/10
Y1 - 2012/10
N2 - Objective: To evaluate the diagnostic value of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) for minor salivary gland tumors in the oral cavity. Materials and methods: Thirty-two patients with minor salivary gland tumors were examined preoperatively using DCE-MRI. Their maximum contrast index (CImax), time of CImax (Tmax), Tpeak; i.e., the time that corresponded to the CImax × 0.90, and washout ratios (WR300 and WR600) were determined from contrast index (CI) curves. We compared these parameters between benign and malignant tumors and among the different histopathological types of minor salivary gland tumors. Then, we categorized the patients' CI curves into four patterns (gradual increase, rapid increase with high washout ratio, rapid increase with low washout, and flat). Results: Statistically significant differences in Tmax (P = 0.004) and Tpeak (P = 0.002) were observed between the benign and malignant tumors. Regarding each histopathological tumor type, significant differences in Tmax (P <0.001), Tpeak (P <0.001), and WR600 (P = 0.026) were observed between the pleomorphic adenomas and mucoepidermoid carcinomas. It was difficult to distinguish between benign and malignant tumors using our CI curve classification because that two-thirds of the cases were classified into the same type (gradual increase). Conclusion: The DCE-MRI parameters of minor salivary gland tumors contributed little to their differential diagnosis compared with those for major salivary gland tumors. During the diagnosis of minor salivary gland tumors, Tmax is useful for distinguishing between benign and malignant tumors.
AB - Objective: To evaluate the diagnostic value of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) for minor salivary gland tumors in the oral cavity. Materials and methods: Thirty-two patients with minor salivary gland tumors were examined preoperatively using DCE-MRI. Their maximum contrast index (CImax), time of CImax (Tmax), Tpeak; i.e., the time that corresponded to the CImax × 0.90, and washout ratios (WR300 and WR600) were determined from contrast index (CI) curves. We compared these parameters between benign and malignant tumors and among the different histopathological types of minor salivary gland tumors. Then, we categorized the patients' CI curves into four patterns (gradual increase, rapid increase with high washout ratio, rapid increase with low washout, and flat). Results: Statistically significant differences in Tmax (P = 0.004) and Tpeak (P = 0.002) were observed between the benign and malignant tumors. Regarding each histopathological tumor type, significant differences in Tmax (P <0.001), Tpeak (P <0.001), and WR600 (P = 0.026) were observed between the pleomorphic adenomas and mucoepidermoid carcinomas. It was difficult to distinguish between benign and malignant tumors using our CI curve classification because that two-thirds of the cases were classified into the same type (gradual increase). Conclusion: The DCE-MRI parameters of minor salivary gland tumors contributed little to their differential diagnosis compared with those for major salivary gland tumors. During the diagnosis of minor salivary gland tumors, Tmax is useful for distinguishing between benign and malignant tumors.
KW - Adenoid cystic carcinoma
KW - Dynamic MRI
KW - Minor salivary gland tumor
KW - MRI
KW - Mucoepidermoid carcinoma
KW - Oral
KW - Pleomorphic adenoma
UR - http://www.scopus.com/inward/record.url?scp=84865264315&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84865264315&partnerID=8YFLogxK
U2 - 10.1016/j.ejrad.2011.11.005
DO - 10.1016/j.ejrad.2011.11.005
M3 - Article
C2 - 22138118
AN - SCOPUS:84865264315
VL - 81
SP - 2684
EP - 2691
JO - Journal of Medical Imaging
JF - Journal of Medical Imaging
SN - 0720-048X
IS - 10
ER -