@article{c79a18738c0648f89a6526eb37d7e649,
title = "Miniaturization and Combinatorial Approach in Organic Electrochemistry",
abstract = "Recent advances in electro-organic chemistry involving miniaturization, integration, and combinatorial chemistry were reviewed. Microelectrode array technology for site-selective electro-organic reactions and addressable libraries provides a direct and unlabeled method for measuring small-molecule-protein interactions. Electrochemical systems using solid-supported bases and acids ({"}site separation{"}) can realize electrolysis without the addition of supporting electrolytes. Well-designed {"}bipolar electrodes{"} have enabled the production of patterned gradient polymer brushes and microfibers. For the display of combinatorial organic electrochemistry, batch and flow electrolysis systems for the optimization and screening of electro-organic reactions as well as the building of chemical libraries for organic compounds are described.",
author = "Koichi Mitsudo and Yuji Kurimoto and Kazuki Yoshioka and Seiji Suga",
note = "Funding Information: Seiji Suga graduated from Nagoya University under the guidance of Professor Ryoji Noyori and received his Ph.D. in 1995. After working as a postdoctoral researcher at the University of Oxford (JSPS Postdoctoral Fellowship for Research Abroad, Prof. Sir Jack E. Baldwin), he moved to Kyoto University as an assistant professor (Prof. Jun-ichi Yoshida{\textquoteright}s research group) in 1996. After being promoted to Lecturer and Associate Professor, he was appointed Professor of Okayama University in 2008. Since 2017, he has been Executive Vice President at the same university. He is conducting research on the transformation of organic compounds based on electron transfer chemistry, flow chemistry, and organocatalysts. Funding Information: This work was supported in part by JSPS KAKENHI (Grant Nos. 16H01155 and 16K05777) and by JST, ACT-C, Japan. Publisher Copyright: {\textcopyright} 2018 American Chemical Society.",
year = "2018",
month = jun,
day = "27",
doi = "10.1021/acs.chemrev.7b00532",
language = "English",
volume = "118",
pages = "5985--5999",
journal = "Chemical Reviews",
issn = "0009-2665",
publisher = "American Chemical Society",
number = "12",
}