Millifolides a-c. new 1,10-seco-guaianolides from the flowers of Achillea millefolium

Yong Li, Zhi Yu Ni, Meng Chu Zhu, Kai Zhang, Yi Bing Wu, Mei Dong, Qing Wen Shi, Chang Hong Huo, Françoise Sauriol, Hiromasa Kiyota, Yu Cheng Gu, Bin Cong

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Ten 1,10-secoguaianolides were isolated from the flowers of Achillea millefolium. Their structures were determined on the basis of spectroscopic methods. Three of them (millifolides A-C) including two dimeric sesquiterpenoids exhibit new skeletons. Seco-tanapartholide A exhibited moderate cell growth inhibitory activity against the human cancer cell line MCF7WT (IC50 = 5:51μm) in vitro.

Original languageEnglish
Pages (from-to)438-446
Number of pages9
JournalZeitschrift fur Naturforschung - Section B Journal of Chemical Sciences
Volume67
Issue number5
DOIs
Publication statusPublished - May 2012
Externally publishedYes

Fingerprint

Cell growth
Cells

Keywords

  • 1,10-Seco-guaianolides
  • Achillea millefolium
  • Cell Growth Inhibition
  • Millifolides A to C
  • Structure Elucidation

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Millifolides a-c. new 1,10-seco-guaianolides from the flowers of Achillea millefolium. / Li, Yong; Ni, Zhi Yu; Zhu, Meng Chu; Zhang, Kai; Wu, Yi Bing; Dong, Mei; Shi, Qing Wen; Huo, Chang Hong; Sauriol, Françoise; Kiyota, Hiromasa; Gu, Yu Cheng; Cong, Bin.

In: Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences, Vol. 67, No. 5, 05.2012, p. 438-446.

Research output: Contribution to journalArticle

Li, Y, Ni, ZY, Zhu, MC, Zhang, K, Wu, YB, Dong, M, Shi, QW, Huo, CH, Sauriol, F, Kiyota, H, Gu, YC & Cong, B 2012, 'Millifolides a-c. new 1,10-seco-guaianolides from the flowers of Achillea millefolium', Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences, vol. 67, no. 5, pp. 438-446. https://doi.org/10.5560/ZNB.2012-0028
Li, Yong ; Ni, Zhi Yu ; Zhu, Meng Chu ; Zhang, Kai ; Wu, Yi Bing ; Dong, Mei ; Shi, Qing Wen ; Huo, Chang Hong ; Sauriol, Françoise ; Kiyota, Hiromasa ; Gu, Yu Cheng ; Cong, Bin. / Millifolides a-c. new 1,10-seco-guaianolides from the flowers of Achillea millefolium. In: Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences. 2012 ; Vol. 67, No. 5. pp. 438-446.
@article{e871422d6ccc48bab653048761d377ab,
title = "Millifolides a-c. new 1,10-seco-guaianolides from the flowers of Achillea millefolium",
abstract = "Ten 1,10-secoguaianolides were isolated from the flowers of Achillea millefolium. Their structures were determined on the basis of spectroscopic methods. Three of them (millifolides A-C) including two dimeric sesquiterpenoids exhibit new skeletons. Seco-tanapartholide A exhibited moderate cell growth inhibitory activity against the human cancer cell line MCF7WT (IC50 = 5:51μm) in vitro.",
keywords = "1,10-Seco-guaianolides, Achillea millefolium, Cell Growth Inhibition, Millifolides A to C, Structure Elucidation",
author = "Yong Li and Ni, {Zhi Yu} and Zhu, {Meng Chu} and Kai Zhang and Wu, {Yi Bing} and Mei Dong and Shi, {Qing Wen} and Huo, {Chang Hong} and Fran{\cc}oise Sauriol and Hiromasa Kiyota and Gu, {Yu Cheng} and Bin Cong",
year = "2012",
month = "5",
doi = "10.5560/ZNB.2012-0028",
language = "English",
volume = "67",
pages = "438--446",
journal = "Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences",
issn = "0932-0776",
publisher = "Verlag der Zeitschrift fur Naturforschung",
number = "5",

}

TY - JOUR

T1 - Millifolides a-c. new 1,10-seco-guaianolides from the flowers of Achillea millefolium

AU - Li, Yong

AU - Ni, Zhi Yu

AU - Zhu, Meng Chu

AU - Zhang, Kai

AU - Wu, Yi Bing

AU - Dong, Mei

AU - Shi, Qing Wen

AU - Huo, Chang Hong

AU - Sauriol, Françoise

AU - Kiyota, Hiromasa

AU - Gu, Yu Cheng

AU - Cong, Bin

PY - 2012/5

Y1 - 2012/5

N2 - Ten 1,10-secoguaianolides were isolated from the flowers of Achillea millefolium. Their structures were determined on the basis of spectroscopic methods. Three of them (millifolides A-C) including two dimeric sesquiterpenoids exhibit new skeletons. Seco-tanapartholide A exhibited moderate cell growth inhibitory activity against the human cancer cell line MCF7WT (IC50 = 5:51μm) in vitro.

AB - Ten 1,10-secoguaianolides were isolated from the flowers of Achillea millefolium. Their structures were determined on the basis of spectroscopic methods. Three of them (millifolides A-C) including two dimeric sesquiterpenoids exhibit new skeletons. Seco-tanapartholide A exhibited moderate cell growth inhibitory activity against the human cancer cell line MCF7WT (IC50 = 5:51μm) in vitro.

KW - 1,10-Seco-guaianolides

KW - Achillea millefolium

KW - Cell Growth Inhibition

KW - Millifolides A to C

KW - Structure Elucidation

UR - http://www.scopus.com/inward/record.url?scp=84862729059&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84862729059&partnerID=8YFLogxK

U2 - 10.5560/ZNB.2012-0028

DO - 10.5560/ZNB.2012-0028

M3 - Article

AN - SCOPUS:84862729059

VL - 67

SP - 438

EP - 446

JO - Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences

JF - Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences

SN - 0932-0776

IS - 5

ER -