Millifolide A, a dimeric ether of degraded sesquiterpene lactones, inhibited the proliferation of human lung cancer cell line A549

Pan Pan Yu; Feng Yu; Wen Zhe Li; Si Ming Wang; Chuan Wang; Mei Dong; Zhi Yu Ni; Yong Li; Hiromasa Kiyota

doi:10.1080/14786419.2021.1922906

Millifolide A, a dimeric ether of degraded sesquiterpene lactones, inhibited the proliferation of human lung cancer cell line A549

Pan Pan Yu, Feng Yu, Wen Zhe Li, Si Ming Wang, Chuan Wang, Mei Dong, Zhi Yu Ni, Yong Li, Hiromasa Kiyota

Research output: Contribution to journal › Article › peer-review

Abstract

The inhibitory effect of three degraded sesquiterpene lactones, iso-seco-tanapartholide, arteludooicinolide A and millifolide A isolated from Achillea millefolium L., on anti-human lung cancer cells was examined using MTT and reporter gene assays. Millifolide A has significant inhibitory effects on the proliferation of human lung cancer cells probably through inducing cell apoptosis.

Original language	English
Journal	Natural Product Research
DOIs	https://doi.org/10.1080/14786419.2021.1922906
Publication status	Accepted/In press - 2021

Keywords

Achillea millefolium L
antiproliferation
apoptosis
human lung cancer cells
millifolide A

ASJC Scopus subject areas

Analytical Chemistry
Biochemistry
Plant Science
Organic Chemistry

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1080/14786419.2021.1922906

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title = "Millifolide A, a dimeric ether of degraded sesquiterpene lactones, inhibited the proliferation of human lung cancer cell line A549",

abstract = "The inhibitory effect of three degraded sesquiterpene lactones, iso-seco-tanapartholide, arteludooicinolide A and millifolide A isolated from Achillea millefolium L., on anti-human lung cancer cells was examined using MTT and reporter gene assays. Millifolide A has significant inhibitory effects on the proliferation of human lung cancer cells probably through inducing cell apoptosis.",

keywords = "Achillea millefolium L, antiproliferation, apoptosis, human lung cancer cells, millifolide A",

author = "Yu, {Pan Pan} and Feng Yu and Li, {Wen Zhe} and Wang, {Si Ming} and Chuan Wang and Mei Dong and Ni, {Zhi Yu} and Yong Li and Hiromasa Kiyota",

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year = "2021",

doi = "10.1080/14786419.2021.1922906",

language = "English",

journal = "Natural Product Research",

issn = "1478-6419",

publisher = "Taylor and Francis Ltd.",

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T1 - Millifolide A, a dimeric ether of degraded sesquiterpene lactones, inhibited the proliferation of human lung cancer cell line A549

AU - Yu, Pan Pan

AU - Yu, Feng

AU - Li, Wen Zhe

AU - Wang, Si Ming

AU - Wang, Chuan

AU - Dong, Mei

AU - Ni, Zhi Yu

AU - Li, Yong

AU - Kiyota, Hiromasa

PY - 2021

Y1 - 2021

N2 - The inhibitory effect of three degraded sesquiterpene lactones, iso-seco-tanapartholide, arteludooicinolide A and millifolide A isolated from Achillea millefolium L., on anti-human lung cancer cells was examined using MTT and reporter gene assays. Millifolide A has significant inhibitory effects on the proliferation of human lung cancer cells probably through inducing cell apoptosis.

AB - The inhibitory effect of three degraded sesquiterpene lactones, iso-seco-tanapartholide, arteludooicinolide A and millifolide A isolated from Achillea millefolium L., on anti-human lung cancer cells was examined using MTT and reporter gene assays. Millifolide A has significant inhibitory effects on the proliferation of human lung cancer cells probably through inducing cell apoptosis.

KW - Achillea millefolium L

KW - antiproliferation

KW - apoptosis

KW - human lung cancer cells

KW - millifolide A

UR - http://www.scopus.com/inward/record.url?scp=85106288002&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85106288002&partnerID=8YFLogxK

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DO - 10.1080/14786419.2021.1922906

M3 - Article

C2 - 33980087

AN - SCOPUS:85106288002

JO - Natural Product Research

JF - Natural Product Research

SN - 1478-6419

ER -

Millifolide A, a dimeric ether of degraded sesquiterpene lactones, inhibited the proliferation of human lung cancer cell line A549

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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