@article{08ebc3ca0a084642b23125a2f84b416f,
title = "Microtubule Response to Tensile Stress Is Curbed by NEK6 to Buffer Growth Variation in the Arabidopsis Hypocotyl",
abstract = "Takatani et al. find that a tubulin kinase depolymerizes a subset of microtubules that best align with mechanical stress in plants. In the corresponding mutant, enhanced response to mechanical stress leads to abnormal shapes. In the wild type, the relative inefficiency in microtubule alignment would instead allow global growth averaging.",
keywords = "Arabidopsis, NIMA-related kinase, growth, mechanical stress, microtubule, morphogenesis, polarity, suboptimality, variability",
author = "Shogo Takatani and St{\'e}phane Verger and Takashi Okamoto and Taku Takahashi and Olivier Hamant and Hiroyasu Motose",
note = "Funding Information: We thank Jan Traas and our colleagues for their comments and feedback on this manuscript, as well as Geoff Wasteneys for triggering this collaboration in 2014. This work was supported by the AgreenSkills+ fellowship program , which has received funding from the European Union{\textquoteright}s Seventh Framework Program under Grant Agreement FP7-609398 ( AgreenSkills+ contract to S.T.), by Human Frontier Science Program Long-Term-Fellowship ( LT000891/2018-L ) to S.T., by the European Research Council ( ERC-2013-CoG-615739 {\textquoteleft}{\textquoteleft}MechanoDevo{\textquoteright}{\textquoteright}) to O.H., by Human Frontier Science Program grant RGP0023/2018 to O.H., by JSPS KAKENHI Grants ( 16K07403 and 19K06709 to H.M.; 16J03501 to S.T.), by the NOVARTIS Foundation (Japan) for the Promotion of Science to H.M., by the Okayama Foundation for Science and Technology to H.M., and by Nakahara Education and Research Support Fund in Okayama University to H.M. Funding Information: We thank Jan Traas and our colleagues for their comments and feedback on this manuscript, as well as Geoff Wasteneys for triggering this collaboration in 2014. This work was supported by the AgreenSkills+ fellowship program, which has received funding from the European Union's Seventh Framework Program under Grant Agreement FP7-609398 (AgreenSkills+ contract to S.T.), by Human Frontier Science Program Long-Term-Fellowship (LT000891/2018-L) to S.T. by the European Research Council (ERC-2013-CoG-615739 ??MechanoDevo??) to O.H. by Human Frontier Science Program grant RGP0023/2018 to O.H. by JSPS KAKENHI Grants (16K07403 and 19K06709 to H.M.; 16J03501 to S.T.), by the NOVARTIS Foundation (Japan) for the Promotion of Science to H.M. by the Okayama Foundation for Science and Technology to H.M. and by Nakahara Education and Research Support Fund in Okayama University to H.M. S.T. S.V. and T.O. performed the experiments. S.T. analyzed the results. T.T. O.H. and H.M. supervised the work. S.T. O.H. and H.M. wrote the article. The authors declare no competing interests. Publisher Copyright: {\textcopyright} 2020 Elsevier Inc.",
year = "2020",
month = apr,
day = "20",
doi = "10.1016/j.cub.2020.02.024",
language = "English",
volume = "30",
pages = "1491--1503.e2",
journal = "Current Biology",
issn = "0960-9822",
publisher = "Cell Press",
number = "8",
}