Microtubule-like properties of the bacterial actin homolog ParM-R1

David Popp; Akihiro Narita; Lin Jie Lee; Mårten Larsson; Robert C. Robinson

doi:10.1074/jbc.M111.319491

Microtubule-like properties of the bacterial actin homolog ParM-R1

David Popp, Akihiro Narita, Lin Jie Lee, Mårten Larsson, Robert C. Robinson

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

Background: ParM-R1 is a filament-forming actin homolog that segregates DNA in bacteria. Results: ParM-R1 exhibits synchronous microtubule-like oscillations between assembly and disassembly and forms asters growing from a centrosome-like nucleus of interconnected nodes. Conclusion: ParM-R1 exhibits microtubule-like properties. Significance: These results imply that the selection pressure to reliably segregate DNA during cell division has led to common mechanisms within diverse segregation machineries.

Original language	English
Pages (from-to)	37078-37088
Number of pages	11
Journal	Journal of Biological Chemistry
Volume	287
Issue number	44
DOIs	https://doi.org/10.1074/jbc.M111.319491
Publication status	Published - Oct 26 2012
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Molecular Biology
Cell Biology

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10.1074/jbc.M111.319491

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abstract = "Background: ParM-R1 is a filament-forming actin homolog that segregates DNA in bacteria. Results: ParM-R1 exhibits synchronous microtubule-like oscillations between assembly and disassembly and forms asters growing from a centrosome-like nucleus of interconnected nodes. Conclusion: ParM-R1 exhibits microtubule-like properties. Significance: These results imply that the selection pressure to reliably segregate DNA during cell division has led to common mechanisms within diverse segregation machineries.",

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AU - Narita, Akihiro

AU - Lee, Lin Jie

AU - Larsson, Mårten

AU - Robinson, Robert C.

PY - 2012/10/26

Y1 - 2012/10/26

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AB - Background: ParM-R1 is a filament-forming actin homolog that segregates DNA in bacteria. Results: ParM-R1 exhibits synchronous microtubule-like oscillations between assembly and disassembly and forms asters growing from a centrosome-like nucleus of interconnected nodes. Conclusion: ParM-R1 exhibits microtubule-like properties. Significance: These results imply that the selection pressure to reliably segregate DNA during cell division has led to common mechanisms within diverse segregation machineries.

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Microtubule-like properties of the bacterial actin homolog ParM-R1

Abstract

ASJC Scopus subject areas

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