Microtubule-like properties of the bacterial actin homolog ParM-R1

David Popp, Akihiro Narita, Lin Jie Lee, Mårten Larsson, Robert C. Robinson

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

Background: ParM-R1 is a filament-forming actin homolog that segregates DNA in bacteria. Results: ParM-R1 exhibits synchronous microtubule-like oscillations between assembly and disassembly and forms asters growing from a centrosome-like nucleus of interconnected nodes. Conclusion: ParM-R1 exhibits microtubule-like properties. Significance: These results imply that the selection pressure to reliably segregate DNA during cell division has led to common mechanisms within diverse segregation machineries.

Original languageEnglish
Pages (from-to)37078-37088
Number of pages11
JournalJournal of Biological Chemistry
Volume287
Issue number44
DOIs
Publication statusPublished - Oct 26 2012

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Cell Biology

Fingerprint Dive into the research topics of 'Microtubule-like properties of the bacterial actin homolog ParM-R1'. Together they form a unique fingerprint.

Cite this