Abstract
This conference proceeding reports a preliminary result regarding a simple technique to fabricate core-shell tetra-arm poly(ethylene glycol) (tetra-PEG) hydrogel microbeads encapsulating insulin-secreting cells using microfluidic emulsification and interfacial coupling reaction of two kinds of tetra-PEG macromonomers at the core-shell interface in the precursor aqueous droplets. Different from conventional PEG-based microbeads formation, in situ gelation system utilizing self-diffusion of the macromonomers in confined microdroplets allowed to prepare tetra-PEG hydrogel microbeads with narrow size distribution under mild gelation condition in the absence of heating and UV irradiation. This technology can be used to generate monodisperse tetra-PEG hydrogel microbeads to encapsulate sensitive cells for regenerative medicines.
| Original language | English |
|---|---|
| Title of host publication | MEMS 2016 - 29th IEEE International Conference on Micro Electro Mechanical Systems |
| Publisher | Institute of Electrical and Electronics Engineers Inc. |
| Pages | 718-720 |
| Number of pages | 3 |
| Volume | 2016-February |
| ISBN (Electronic) | 9781509019731 |
| DOIs | |
| Publication status | Published - Feb 26 2016 |
| Externally published | Yes |
| Event | 29th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2016 - Shanghai, China Duration: Jan 24 2016 → Jan 28 2016 |
Other
| Other | 29th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2016 |
|---|---|
| Country | China |
| City | Shanghai |
| Period | 1/24/16 → 1/28/16 |
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ASJC Scopus subject areas
- Electrical and Electronic Engineering
- Mechanical Engineering
- Condensed Matter Physics
- Electronic, Optical and Magnetic Materials