Microfluidic extraction of docosahexaenoic acid ethyl ester: Comparison between slug flow and emulsion

Eiji Kamio; Yu Seike; Hidekazu Yoshizawa; Hideto Matsuyama; Tsutomu Ono

doi:10.1021/ie102207c

Microfluidic extraction of docosahexaenoic acid ethyl ester: Comparison between slug flow and emulsion

Eiji Kamio, Yu Seike, Hidekazu Yoshizawa, Hideto Matsuyama, Tsutomu Ono

Research output: Contribution to journal › Article › peer-review

26 Citations (Scopus)

Abstract

Microfluidic liquid-liquid extraction of the ethyl ester of docosahexaenoic acid (DHA-Et) with silver ions was investigated using slug flow and a water-in-oil (W/O) emulsion as specific flow patterns possessing large interfacial areas. To compare the extraction rates of both systems, slug flow and a W/O emulsion with similar specific interfacial areas were prepared. Extraction rates for the systems were the same at 298 K. However, at 268 K, slug flow had a faster extraction rate than the W/O emulsion. Theoretical calculation follows the results for both systems at 298 K and for the slug flow system at 268 K, suggesting that the emulsion stabilizer inhibits complex formation between DHA-Et and silver ions at the O/W interface. A reduction in extraction rate was observed in the slug flow system at 268 K when the emulsion stabilizer was used. Slug flow can be prepared without stabilizer, offering advantages over emulsions in microfluidic extraction.

Original language	English
Pages (from-to)	6915-6924
Number of pages	10
Journal	Industrial and Engineering Chemistry Research
Volume	50
Issue number	11
DOIs	https://doi.org/10.1021/ie102207c
Publication status	Published - Jun 1 2011

ASJC Scopus subject areas

Chemistry(all)
Chemical Engineering(all)
Industrial and Manufacturing Engineering

Access to Document

10.1021/ie102207c

Fingerprint Dive into the research topics of 'Microfluidic extraction of docosahexaenoic acid ethyl ester: Comparison between slug flow and emulsion'. Together they form a unique fingerprint.

Cite this

@article{cf3e7932ad9e4d86a1204018121bbe0c,

title = "Microfluidic extraction of docosahexaenoic acid ethyl ester: Comparison between slug flow and emulsion",

abstract = "Microfluidic liquid-liquid extraction of the ethyl ester of docosahexaenoic acid (DHA-Et) with silver ions was investigated using slug flow and a water-in-oil (W/O) emulsion as specific flow patterns possessing large interfacial areas. To compare the extraction rates of both systems, slug flow and a W/O emulsion with similar specific interfacial areas were prepared. Extraction rates for the systems were the same at 298 K. However, at 268 K, slug flow had a faster extraction rate than the W/O emulsion. Theoretical calculation follows the results for both systems at 298 K and for the slug flow system at 268 K, suggesting that the emulsion stabilizer inhibits complex formation between DHA-Et and silver ions at the O/W interface. A reduction in extraction rate was observed in the slug flow system at 268 K when the emulsion stabilizer was used. Slug flow can be prepared without stabilizer, offering advantages over emulsions in microfluidic extraction.",

author = "Eiji Kamio and Yu Seike and Hidekazu Yoshizawa and Hideto Matsuyama and Tsutomu Ono",

year = "2011",

month = jun,

day = "1",

doi = "10.1021/ie102207c",

language = "English",

volume = "50",

pages = "6915--6924",

journal = "PRODUCT R AND D.",

issn = "0888-5885",

publisher = "American Chemical Society",

number = "11",

}

TY - JOUR

T1 - Microfluidic extraction of docosahexaenoic acid ethyl ester

T2 - Comparison between slug flow and emulsion

AU - Kamio, Eiji

AU - Seike, Yu

AU - Yoshizawa, Hidekazu

AU - Matsuyama, Hideto

AU - Ono, Tsutomu

PY - 2011/6/1

Y1 - 2011/6/1

N2 - Microfluidic liquid-liquid extraction of the ethyl ester of docosahexaenoic acid (DHA-Et) with silver ions was investigated using slug flow and a water-in-oil (W/O) emulsion as specific flow patterns possessing large interfacial areas. To compare the extraction rates of both systems, slug flow and a W/O emulsion with similar specific interfacial areas were prepared. Extraction rates for the systems were the same at 298 K. However, at 268 K, slug flow had a faster extraction rate than the W/O emulsion. Theoretical calculation follows the results for both systems at 298 K and for the slug flow system at 268 K, suggesting that the emulsion stabilizer inhibits complex formation between DHA-Et and silver ions at the O/W interface. A reduction in extraction rate was observed in the slug flow system at 268 K when the emulsion stabilizer was used. Slug flow can be prepared without stabilizer, offering advantages over emulsions in microfluidic extraction.

AB - Microfluidic liquid-liquid extraction of the ethyl ester of docosahexaenoic acid (DHA-Et) with silver ions was investigated using slug flow and a water-in-oil (W/O) emulsion as specific flow patterns possessing large interfacial areas. To compare the extraction rates of both systems, slug flow and a W/O emulsion with similar specific interfacial areas were prepared. Extraction rates for the systems were the same at 298 K. However, at 268 K, slug flow had a faster extraction rate than the W/O emulsion. Theoretical calculation follows the results for both systems at 298 K and for the slug flow system at 268 K, suggesting that the emulsion stabilizer inhibits complex formation between DHA-Et and silver ions at the O/W interface. A reduction in extraction rate was observed in the slug flow system at 268 K when the emulsion stabilizer was used. Slug flow can be prepared without stabilizer, offering advantages over emulsions in microfluidic extraction.

UR - http://www.scopus.com/inward/record.url?scp=79960007631&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=79960007631&partnerID=8YFLogxK

U2 - 10.1021/ie102207c

DO - 10.1021/ie102207c

M3 - Article

AN - SCOPUS:79960007631

VL - 50

SP - 6915

EP - 6924

JO - PRODUCT R AND D.

JF - PRODUCT R AND D.

SN - 0888-5885

IS - 11

ER -