TY - JOUR
T1 - Microfluidic extraction of docosahexaenoic acid ethyl ester
T2 - Comparison between slug flow and emulsion
AU - Kamio, Eiji
AU - Seike, Yu
AU - Yoshizawa, Hidekazu
AU - Matsuyama, Hideto
AU - Ono, Tsutomu
PY - 2011/6/1
Y1 - 2011/6/1
N2 - Microfluidic liquid-liquid extraction of the ethyl ester of docosahexaenoic acid (DHA-Et) with silver ions was investigated using slug flow and a water-in-oil (W/O) emulsion as specific flow patterns possessing large interfacial areas. To compare the extraction rates of both systems, slug flow and a W/O emulsion with similar specific interfacial areas were prepared. Extraction rates for the systems were the same at 298 K. However, at 268 K, slug flow had a faster extraction rate than the W/O emulsion. Theoretical calculation follows the results for both systems at 298 K and for the slug flow system at 268 K, suggesting that the emulsion stabilizer inhibits complex formation between DHA-Et and silver ions at the O/W interface. A reduction in extraction rate was observed in the slug flow system at 268 K when the emulsion stabilizer was used. Slug flow can be prepared without stabilizer, offering advantages over emulsions in microfluidic extraction.
AB - Microfluidic liquid-liquid extraction of the ethyl ester of docosahexaenoic acid (DHA-Et) with silver ions was investigated using slug flow and a water-in-oil (W/O) emulsion as specific flow patterns possessing large interfacial areas. To compare the extraction rates of both systems, slug flow and a W/O emulsion with similar specific interfacial areas were prepared. Extraction rates for the systems were the same at 298 K. However, at 268 K, slug flow had a faster extraction rate than the W/O emulsion. Theoretical calculation follows the results for both systems at 298 K and for the slug flow system at 268 K, suggesting that the emulsion stabilizer inhibits complex formation between DHA-Et and silver ions at the O/W interface. A reduction in extraction rate was observed in the slug flow system at 268 K when the emulsion stabilizer was used. Slug flow can be prepared without stabilizer, offering advantages over emulsions in microfluidic extraction.
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U2 - 10.1021/ie102207c
DO - 10.1021/ie102207c
M3 - Article
AN - SCOPUS:79960007631
VL - 50
SP - 6915
EP - 6924
JO - Industrial & Engineering Chemistry Product Research and Development
JF - Industrial & Engineering Chemistry Product Research and Development
SN - 0888-5885
IS - 11
ER -