Metachromins L-Q, new sesquiterpenoid quinones with an amino acid residue from sponge Spongia sp.

Yohei Takahashi, Takaaki Kubota, Jane Fromont, Jun'ichi Kobayashi

Research output: Contribution to journalArticlepeer-review

27 Citations (Scopus)

Abstract

Six new sesquiterpenoid quinones with an amino acid residue, metachromins L-Q (1-6), have been isolated from an Okinawan marine sponge Spongia sp. The structures and stereochemistry of 1-6 were elucidated on the basis of the spectroscopic data and chemical correlations. Metachromins L (1) and M (2) showed modest cytotoxicity.

Original languageEnglish
Pages (from-to)8770-8773
Number of pages4
JournalTetrahedron
Volume63
Issue number36
DOIs
Publication statusPublished - Sep 3 2007
Externally publishedYes

Keywords

  • Metachromins L-Q
  • Sesquiterpenoid quinones
  • Sponge
  • Spongia sp

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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