Membranous labyrinth volumes in normal ears and Ménière disease

A three-dimensional reconstruction study

Norimasa Morita, Shin Kariya, Armin Farajzadeh Deroee, Sebahattin Cureoglu, Shigenobu Nomiya, Rie Nomiya, Tamotsu Harada, Michael M. Paparella

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

Objectives: The purpose of this study was to determine the normal volume ranges of cochlear duct, saccule, and utricle, and to assess endolymphatic hydrops in Ménière disease. Study Design: Retrospective temporal bone study. Methods: Three-dimensional (3-D) images of membranous labyrinth were reconstructed from 31 normal temporal bones, six temporal bones from three patients with bilateral Ménière disease, and 16 temporal bones from eight patients with unilateral Ménière disease. Volumes of each part of membranous labyrinth were measured in each temporal bone group after 3-D reconstruction. Results: The mean volumes and upper normal volume limits (over the 95% confidence interval) of the cochlear duct, saccule, and utricle were 7.67 and 9.77 mm3, 2.42 and 3.68 mm3, and 10.65 and 16.45 mm3, respectively. All three patients with bilateral Ménière disease showed endolymphatic hydrops (excess of volume over normal limits) in both ears. Of eight patients with unilateral Ménière disease, five had no symptom in the contralateral ear, whereas three patients had histories of progression from unilateral to bilateral Ménière disease 13-21 years after the initial onset. All of the diseased and three of eight contralateral ears showed endolymphatic hydrops. In contrast, no hydrops was observed in any part of the membranous labyrinth in asymptomatic ears. Conclusions: Our findings suggest that cochleosaccular hydrops is a sensitive finding in Ménière disease. In addition, the volume data obtained from this study could be useful as a standard value for the assessment of hydrops in diagnostic imaging of the inner ear in Ménière disease.

Original languageEnglish
Pages (from-to)2216-2220
Number of pages5
JournalLaryngoscope
Volume119
Issue number11
DOIs
Publication statusPublished - Nov 2009

Fingerprint

Ear Diseases
Inner Ear
Temporal Bone
Endolymphatic Hydrops
Ear
Cochlear Duct
Saccule and Utricle
Edema
Three-Dimensional Imaging
Diagnostic Imaging
Reference Values
Retrospective Studies
Confidence Intervals

Keywords

  • Endolymphatic hydrops
  • Human temporal bone
  • Ménière disease
  • Membranous labyrinth
  • Three-dimensional reconstruction
  • Volume measurement

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Morita, N., Kariya, S., Deroee, A. F., Cureoglu, S., Nomiya, S., Nomiya, R., ... Paparella, M. M. (2009). Membranous labyrinth volumes in normal ears and Ménière disease: A three-dimensional reconstruction study. Laryngoscope, 119(11), 2216-2220. https://doi.org/10.1002/lary.20723

Membranous labyrinth volumes in normal ears and Ménière disease : A three-dimensional reconstruction study. / Morita, Norimasa; Kariya, Shin; Deroee, Armin Farajzadeh; Cureoglu, Sebahattin; Nomiya, Shigenobu; Nomiya, Rie; Harada, Tamotsu; Paparella, Michael M.

In: Laryngoscope, Vol. 119, No. 11, 11.2009, p. 2216-2220.

Research output: Contribution to journalArticle

Morita, N, Kariya, S, Deroee, AF, Cureoglu, S, Nomiya, S, Nomiya, R, Harada, T & Paparella, MM 2009, 'Membranous labyrinth volumes in normal ears and Ménière disease: A three-dimensional reconstruction study', Laryngoscope, vol. 119, no. 11, pp. 2216-2220. https://doi.org/10.1002/lary.20723
Morita, Norimasa ; Kariya, Shin ; Deroee, Armin Farajzadeh ; Cureoglu, Sebahattin ; Nomiya, Shigenobu ; Nomiya, Rie ; Harada, Tamotsu ; Paparella, Michael M. / Membranous labyrinth volumes in normal ears and Ménière disease : A three-dimensional reconstruction study. In: Laryngoscope. 2009 ; Vol. 119, No. 11. pp. 2216-2220.
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abstract = "Objectives: The purpose of this study was to determine the normal volume ranges of cochlear duct, saccule, and utricle, and to assess endolymphatic hydrops in M{\'e}ni{\`e}re disease. Study Design: Retrospective temporal bone study. Methods: Three-dimensional (3-D) images of membranous labyrinth were reconstructed from 31 normal temporal bones, six temporal bones from three patients with bilateral M{\'e}ni{\`e}re disease, and 16 temporal bones from eight patients with unilateral M{\'e}ni{\`e}re disease. Volumes of each part of membranous labyrinth were measured in each temporal bone group after 3-D reconstruction. Results: The mean volumes and upper normal volume limits (over the 95{\%} confidence interval) of the cochlear duct, saccule, and utricle were 7.67 and 9.77 mm3, 2.42 and 3.68 mm3, and 10.65 and 16.45 mm3, respectively. All three patients with bilateral M{\'e}ni{\`e}re disease showed endolymphatic hydrops (excess of volume over normal limits) in both ears. Of eight patients with unilateral M{\'e}ni{\`e}re disease, five had no symptom in the contralateral ear, whereas three patients had histories of progression from unilateral to bilateral M{\'e}ni{\`e}re disease 13-21 years after the initial onset. All of the diseased and three of eight contralateral ears showed endolymphatic hydrops. In contrast, no hydrops was observed in any part of the membranous labyrinth in asymptomatic ears. Conclusions: Our findings suggest that cochleosaccular hydrops is a sensitive finding in M{\'e}ni{\`e}re disease. In addition, the volume data obtained from this study could be useful as a standard value for the assessment of hydrops in diagnostic imaging of the inner ear in M{\'e}ni{\`e}re disease.",
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