Medusozoan genomes inform the evolution of the jellyfish body plan

Konstantin Khalturin, Chuya Shinzato, Maria Khalturina, Mayuko Hamada, Manabu Fujie, Ryo Koyanagi, Miyuki Kanda, Hiroki Goto, Friederike Anton-Erxleben, Masaya Toyokawa, Sho Toshino, Noriyuki Satoh

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Cnidarians are astonishingly diverse in body form and lifestyle, including the presence of a jellyfish stage in medusozoans and its absence in anthozoans. Here, we sequence the genomes of Aurelia aurita (a scyphozoan) and Morbakka virulenta (a cubozoan) to understand the molecular mechanisms responsible for the origin of the jellyfish body plan. We show that the magnitude of genetic differences between the two jellyfish types is equivalent, on average, to the level of genetic differences between humans and sea urchins in the bilaterian lineage. About one-third of Aurelia genes with jellyfish-specific expression have no matches in the genomes of the coral and sea anemone, indicating that the polyp-to-jellyfish transition requires a combination of conserved and novel, medusozoa-specific genes. While no genomic region is specifically associated with the ability to produce a jellyfish stage, the arrangement of genes involved in the development of a nematocyte—a phylum-specific cell type—is highly structured and conserved in cnidarian genomes; thus, it represents a phylotypic gene cluster.

Original languageEnglish
Pages (from-to)811-822
Number of pages12
JournalNature Ecology and Evolution
Volume3
Issue number5
DOIs
Publication statusPublished - May 1 2019

Fingerprint

jellyfish
Scyphozoa
genome
gene
Anthozoa
Cnidaria
polyp
genes
Echinoidea
multigene family
lifestyle
plan
corals
coral
genomics

ASJC Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics
  • Ecology

Cite this

Khalturin, K., Shinzato, C., Khalturina, M., Hamada, M., Fujie, M., Koyanagi, R., ... Satoh, N. (2019). Medusozoan genomes inform the evolution of the jellyfish body plan. Nature Ecology and Evolution, 3(5), 811-822. https://doi.org/10.1038/s41559-019-0853-y

Medusozoan genomes inform the evolution of the jellyfish body plan. / Khalturin, Konstantin; Shinzato, Chuya; Khalturina, Maria; Hamada, Mayuko; Fujie, Manabu; Koyanagi, Ryo; Kanda, Miyuki; Goto, Hiroki; Anton-Erxleben, Friederike; Toyokawa, Masaya; Toshino, Sho; Satoh, Noriyuki.

In: Nature Ecology and Evolution, Vol. 3, No. 5, 01.05.2019, p. 811-822.

Research output: Contribution to journalArticle

Khalturin, K, Shinzato, C, Khalturina, M, Hamada, M, Fujie, M, Koyanagi, R, Kanda, M, Goto, H, Anton-Erxleben, F, Toyokawa, M, Toshino, S & Satoh, N 2019, 'Medusozoan genomes inform the evolution of the jellyfish body plan', Nature Ecology and Evolution, vol. 3, no. 5, pp. 811-822. https://doi.org/10.1038/s41559-019-0853-y
Khalturin, Konstantin ; Shinzato, Chuya ; Khalturina, Maria ; Hamada, Mayuko ; Fujie, Manabu ; Koyanagi, Ryo ; Kanda, Miyuki ; Goto, Hiroki ; Anton-Erxleben, Friederike ; Toyokawa, Masaya ; Toshino, Sho ; Satoh, Noriyuki. / Medusozoan genomes inform the evolution of the jellyfish body plan. In: Nature Ecology and Evolution. 2019 ; Vol. 3, No. 5. pp. 811-822.
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