TY - JOUR
T1 - Mechanomedicine
T2 - Applications of mechanobiology to medical sciences and next-generation medical technologies
AU - Naruse, Keiji
N1 - Funding Information:
This work was supported by Grants-in-aid for Scientific Research (S) (26220203) and by Grant-in-Aid for Exploratory Research (17K20108) from the Ministry of Education, Science, Sports and Culture of Japan.
PY - 2018
Y1 - 2018
N2 - Mechanical stress underlies most aspects of cell and organismal biology. Mechanomedicine is a field of biology that seeks to understand molecular, cellular, tissue, organ, and individual responses to mechanical stimuli and aims to apply the gained knowledge to improve health. Combining biology and engineering, we explore research areas including mechanosensitive ion channels, heart failure, and regenerative medicine. This review will describe our findings in mechanobiology, our establishment of a joint venture business as we developed devices responding to medical needs, and our alliance with other companies.
AB - Mechanical stress underlies most aspects of cell and organismal biology. Mechanomedicine is a field of biology that seeks to understand molecular, cellular, tissue, organ, and individual responses to mechanical stimuli and aims to apply the gained knowledge to improve health. Combining biology and engineering, we explore research areas including mechanosensitive ion channels, heart failure, and regenerative medicine. This review will describe our findings in mechanobiology, our establishment of a joint venture business as we developed devices responding to medical needs, and our alliance with other companies.
KW - Bioventure
KW - Hemostat
KW - Mechanobiology
KW - Stretch-activated ion channel
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U2 - 10.1540/JSMR.54.83
DO - 10.1540/JSMR.54.83
M3 - Review article
C2 - 30210090
AN - SCOPUS:85056579968
VL - 54
SP - 83
EP - 90
JO - Journal of Smooth Muscle Research
JF - Journal of Smooth Muscle Research
SN - 0916-8737
ER -