Abstract
Understanding and overcoming mechanisms of cancer escape from immunosurveillance have long been a major focus of cancer immunotherapy. These escape mechanisms are very complex, including cancer-derived factors, factors derived from host cells surrounding cancer nests, and factors derived through the interaction between cancer cells and host cells in the hypoxic state. This report mainly describes recent various immunosuppressive factors. Cancer immunotherapy will be best performed concomitantly with mechanisms blocking cancer escape.
| Original language | English |
|---|---|
| Pages (from-to) | 279-294 |
| Number of pages | 16 |
| Journal | Biotherapy |
| Volume | 18 |
| Issue number | 4 |
| Publication status | Published - Jul 1 2004 |
Keywords
- Cancer escape
- Cancer immunotherapy
- Immunosurveillance
ASJC Scopus subject areas
- Oncology
- Cancer Research
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Cite this
Orita, K., Gochi, A., Nakamura, S., & Motoda, R. (2004). Mechanisms of cancer escape from immunosurveillance. Biotherapy, 18(4), 279-294.