Measurement of motor unit action potential in ischemic muscle using intramuscular probe

Hisao Oka, Hiromi Isshiki, P. Åke Öberg

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Under the local ischemia, the supply of sufficient oxygen and energy sources such as free fatty acid and glucose become difficult. This also affects the electrical properties of a cell membrane and it seems to be also concerned in action potential propagation velocity on the muscle fibre. In order to measure muscle function under the local ischemia, an intramuscular probe and measurement system were developed. This probe is composed of optical fiber which measures blood flow and 10 platinum fine electrodes for the action potential measurement. In gastrocnemius of rat, the action potential and blood flow were measured using this probe. The popliteal artery was ligated, and tibial nerve was electro-stimulated. With the advance of the ischemia, the potential propagation velocity, which was calculated from action potential wave got between two electrodes, gradually decreased after the ligation. In all cases of several experiments, the propagation velocity was decreased.

Original languageEnglish
Title of host publicationAPBME 2003 - IEEE EMBS Asian-Pacific Conference on Biomedical Engineering 2003
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages234-235
Number of pages2
ISBN (Electronic)0780379438, 9780780379435
DOIs
Publication statusPublished - Jan 1 2003
EventIEEE EMBS Asian-Pacific Conference on Biomedical Engineering 2003, APBME 2003 - Kyoto-Osaka-Nara, Japan
Duration: Oct 20 2003Oct 22 2003

Publication series

NameAPBME 2003 - IEEE EMBS Asian-Pacific Conference on Biomedical Engineering 2003

Other

OtherIEEE EMBS Asian-Pacific Conference on Biomedical Engineering 2003, APBME 2003
CountryJapan
CityKyoto-Osaka-Nara
Period10/20/0310/22/03

Keywords

  • Action potential
  • Ischemia
  • Muscle fibre

ASJC Scopus subject areas

  • Biomedical Engineering

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    Oka, H., Isshiki, H., & Öberg, P. Å. (2003). Measurement of motor unit action potential in ischemic muscle using intramuscular probe. In APBME 2003 - IEEE EMBS Asian-Pacific Conference on Biomedical Engineering 2003 (pp. 234-235). [1302669] (APBME 2003 - IEEE EMBS Asian-Pacific Conference on Biomedical Engineering 2003). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/APBME.2003.1302669