Measurement of lumbar spinal bone mineral density in preterm infants by dual-energy x-ray absorptiometry

Hirokazu Tsukahara, Masakatsu Sudo, Minoru Umezaki, Yasushi Fujii, Masanori Kuriyama, Kazutaka Yamamoto, Yasushi Ishii

Research output: Contribution to journalArticle

48 Citations (Scopus)

Abstract

Lumbar spinal bone mineral density (BMD) was measured in 40 preterm infants by dual-energy X-ray absorptiometry (DXA). During the first several months of life, their BMD was considerably lower than that of normal term infants and the osteopenia was more pronounced in the more preterm and smaller infants. Weak (inverse) correlations were found be-tween the BMD and urinary calcium/creatinine or tubular phosphorus reabsorption ratio. Rickets-like changes in the forearm bones did not predict the greater spinal osteopenia. Follow-up study was performed in 10 preterms. In 3 of the 4 who underwent the last DXA between 8 and 12 months, BMD had improved remarkably. Our present study shows the potential of DXA for the assessment and management of osteopenia of prematurity.

Original languageEnglish
Pages (from-to)96-103
Number of pages8
JournalNeonatology
Volume64
Issue number2-3
DOIs
Publication statusPublished - 1993
Externally publishedYes

Fingerprint

Premature Infants
Bone Density
Metabolic Bone Diseases
Photon Absorptiometry
X-Rays
Rickets
Polysorbates
Forearm
Phosphorus
Creatinine
Calcium
Bone and Bones

Keywords

  • Bone mineral density
  • Dual-energy X-ray absorptiometry
  • Lumbar spine
  • Osteopenia of prematurity
  • Preterm infants

ASJC Scopus subject areas

  • Developmental Biology
  • Pediatrics, Perinatology, and Child Health

Cite this

Measurement of lumbar spinal bone mineral density in preterm infants by dual-energy x-ray absorptiometry. / Tsukahara, Hirokazu; Sudo, Masakatsu; Umezaki, Minoru; Fujii, Yasushi; Kuriyama, Masanori; Yamamoto, Kazutaka; Ishii, Yasushi.

In: Neonatology, Vol. 64, No. 2-3, 1993, p. 96-103.

Research output: Contribution to journalArticle

Tsukahara, H, Sudo, M, Umezaki, M, Fujii, Y, Kuriyama, M, Yamamoto, K & Ishii, Y 1993, 'Measurement of lumbar spinal bone mineral density in preterm infants by dual-energy x-ray absorptiometry', Neonatology, vol. 64, no. 2-3, pp. 96-103. https://doi.org/10.1159/000243978
Tsukahara, Hirokazu ; Sudo, Masakatsu ; Umezaki, Minoru ; Fujii, Yasushi ; Kuriyama, Masanori ; Yamamoto, Kazutaka ; Ishii, Yasushi. / Measurement of lumbar spinal bone mineral density in preterm infants by dual-energy x-ray absorptiometry. In: Neonatology. 1993 ; Vol. 64, No. 2-3. pp. 96-103.
@article{5533cf3ca689471f843bf97f441f5130,
title = "Measurement of lumbar spinal bone mineral density in preterm infants by dual-energy x-ray absorptiometry",
abstract = "Lumbar spinal bone mineral density (BMD) was measured in 40 preterm infants by dual-energy X-ray absorptiometry (DXA). During the first several months of life, their BMD was considerably lower than that of normal term infants and the osteopenia was more pronounced in the more preterm and smaller infants. Weak (inverse) correlations were found be-tween the BMD and urinary calcium/creatinine or tubular phosphorus reabsorption ratio. Rickets-like changes in the forearm bones did not predict the greater spinal osteopenia. Follow-up study was performed in 10 preterms. In 3 of the 4 who underwent the last DXA between 8 and 12 months, BMD had improved remarkably. Our present study shows the potential of DXA for the assessment and management of osteopenia of prematurity.",
keywords = "Bone mineral density, Dual-energy X-ray absorptiometry, Lumbar spine, Osteopenia of prematurity, Preterm infants",
author = "Hirokazu Tsukahara and Masakatsu Sudo and Minoru Umezaki and Yasushi Fujii and Masanori Kuriyama and Kazutaka Yamamoto and Yasushi Ishii",
year = "1993",
doi = "10.1159/000243978",
language = "English",
volume = "64",
pages = "96--103",
journal = "Neonatology",
issn = "1661-7800",
publisher = "S. Karger AG",
number = "2-3",

}

TY - JOUR

T1 - Measurement of lumbar spinal bone mineral density in preterm infants by dual-energy x-ray absorptiometry

AU - Tsukahara, Hirokazu

AU - Sudo, Masakatsu

AU - Umezaki, Minoru

AU - Fujii, Yasushi

AU - Kuriyama, Masanori

AU - Yamamoto, Kazutaka

AU - Ishii, Yasushi

PY - 1993

Y1 - 1993

N2 - Lumbar spinal bone mineral density (BMD) was measured in 40 preterm infants by dual-energy X-ray absorptiometry (DXA). During the first several months of life, their BMD was considerably lower than that of normal term infants and the osteopenia was more pronounced in the more preterm and smaller infants. Weak (inverse) correlations were found be-tween the BMD and urinary calcium/creatinine or tubular phosphorus reabsorption ratio. Rickets-like changes in the forearm bones did not predict the greater spinal osteopenia. Follow-up study was performed in 10 preterms. In 3 of the 4 who underwent the last DXA between 8 and 12 months, BMD had improved remarkably. Our present study shows the potential of DXA for the assessment and management of osteopenia of prematurity.

AB - Lumbar spinal bone mineral density (BMD) was measured in 40 preterm infants by dual-energy X-ray absorptiometry (DXA). During the first several months of life, their BMD was considerably lower than that of normal term infants and the osteopenia was more pronounced in the more preterm and smaller infants. Weak (inverse) correlations were found be-tween the BMD and urinary calcium/creatinine or tubular phosphorus reabsorption ratio. Rickets-like changes in the forearm bones did not predict the greater spinal osteopenia. Follow-up study was performed in 10 preterms. In 3 of the 4 who underwent the last DXA between 8 and 12 months, BMD had improved remarkably. Our present study shows the potential of DXA for the assessment and management of osteopenia of prematurity.

KW - Bone mineral density

KW - Dual-energy X-ray absorptiometry

KW - Lumbar spine

KW - Osteopenia of prematurity

KW - Preterm infants

UR - http://www.scopus.com/inward/record.url?scp=0027507812&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0027507812&partnerID=8YFLogxK

U2 - 10.1159/000243978

DO - 10.1159/000243978

M3 - Article

C2 - 8260552

AN - SCOPUS:0027507812

VL - 64

SP - 96

EP - 103

JO - Neonatology

JF - Neonatology

SN - 1661-7800

IS - 2-3

ER -