TY - JOUR
T1 - Marsupialisation for keratocystic odontogenic tumours in the mandible
T2 - Longitudinal image analysis of tumour size using 3D visualised CT scans
AU - Shudou, H.
AU - Sasaki, M.
AU - Yamashiro, T.
AU - Tsunomachi, S.
AU - Takenoshita, Y.
AU - Kubota, Y.
AU - Ninomiya, T.
AU - Kawazu, T.
AU - Mori, Y.
PY - 2012/3/1
Y1 - 2012/3/1
N2 - The purpose of this study was to determine how keratocystic odontogenic tumours (KCOTs) in the mandible are reduced during marsupialisation, and to predict the best time for secondary enucleation by analysing computed tomography (CT) images. 15 patients with KCOTs were treated with marsupialisation surgery, and 42 series of CT data taken during the marsupialisation process were analysed. CT data were reconstructed in three-dimensional (3D) images. The 3D images were used to measure the diameter and volume, and to analyse the changes that occurred after marsupialisation. Marsupialised KCOTs tended to be reduced equally towards the window in the tumour. The amount of volume reduction per day (V r) was reduced in proportion to the volume (V) with the formula V r = -0.0029 × V. The formula manipulation for V was V = V 0 × e -0.0029t (t = duration after marsupialisaton (day)). The volume of marsupialised KCOTs was reduced by half over a 239 day cycle. These results demonstrate that the future shape of marsupialised mandibular KCOTs, under good control, could be predicted with significant accuracy using CT data. This prediction could decrease the prolonged marsupialisation state in patients with KCOTs.
AB - The purpose of this study was to determine how keratocystic odontogenic tumours (KCOTs) in the mandible are reduced during marsupialisation, and to predict the best time for secondary enucleation by analysing computed tomography (CT) images. 15 patients with KCOTs were treated with marsupialisation surgery, and 42 series of CT data taken during the marsupialisation process were analysed. CT data were reconstructed in three-dimensional (3D) images. The 3D images were used to measure the diameter and volume, and to analyse the changes that occurred after marsupialisation. Marsupialised KCOTs tended to be reduced equally towards the window in the tumour. The amount of volume reduction per day (V r) was reduced in proportion to the volume (V) with the formula V r = -0.0029 × V. The formula manipulation for V was V = V 0 × e -0.0029t (t = duration after marsupialisaton (day)). The volume of marsupialised KCOTs was reduced by half over a 239 day cycle. These results demonstrate that the future shape of marsupialised mandibular KCOTs, under good control, could be predicted with significant accuracy using CT data. This prediction could decrease the prolonged marsupialisation state in patients with KCOTs.
KW - decompression
KW - keratocystic odontogenic tumour
KW - marsupialisation
UR - http://www.scopus.com/inward/record.url?scp=84858148884&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84858148884&partnerID=8YFLogxK
U2 - 10.1016/j.ijom.2011.10.015
DO - 10.1016/j.ijom.2011.10.015
M3 - Article
C2 - 22113115
AN - SCOPUS:84858148884
VL - 41
SP - 290
EP - 296
JO - International Journal of Oral and Maxillofacial Surgery
JF - International Journal of Oral and Maxillofacial Surgery
SN - 0901-5027
IS - 3
ER -