Marital status and non-small cell lung cancer survival: The Lung Cancer Database Project in Japan

Kumi Saito-Nakaya, Naoki Nakaya, Tatsuo Akechi, Masatoshi Inagaki, Mariko Asai, Koichi Goto, Kanji Nagai, Yutaka Nishiwaki, Shoichiro Tsugane, Shin Fukudo, Yosuke Uchitomi

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Objective: Previous studies have suggested that marital status is associated with survival from lung cancer; however, its association is not conclusive. The association between marital status and survival in Japanese patients with non-small cell lung cancer (NSCLC) was prospectively investigated. Methods: Between July 1999 and July 2004, a total of 1230 NSCLC patients were enrolled. The baseline survey consisted of the collection of clinical information and various demographic data, including marital status. A Cox regression model was used to estimate the hazards ratio (HR) of all-cause mortality adjustments for age, BMI, education level, performance status, histology type, clinical stage, smoking status, choice of definitive treatment, and depression. Results: The multivariable adjusted HR of male widowed patients versus male married patients was 1.7 (95% confidence interval = 1.2-2.5, p = 0.005). However, no significant increased risk of death in female widowed patients compared with female married patients was observed (HR = 0.7, 95% confidence interval = 0.5-1.1, p = 0.15). With regard to separated/divorced and single patients no significant increased risk of death in male and/or female compared with married patients was observed. Conclusions: The present data suggest that male widowed patients with NSCLC have a higher mortality rate than male married patients with NSCLC, after controlling for various factors.

Original languageEnglish
Pages (from-to)869-876
Number of pages8
JournalPsycho-Oncology
Volume17
Issue number9
DOIs
Publication statusPublished - Sep 2008
Externally publishedYes

Fingerprint

Marital Status
Non-Small Cell Lung Carcinoma
Lung Neoplasms
Japan
Databases
Survival
Widowhood
Confidence Intervals
Divorce
Mortality
Proportional Hazards Models
Histology
Smoking
Demography
Depression
Education

Keywords

  • Marital status
  • Non-small cell lung cancer
  • Prospective study
  • Survival

ASJC Scopus subject areas

  • Oncology
  • Psychiatry and Mental health
  • Experimental and Cognitive Psychology

Cite this

Saito-Nakaya, K., Nakaya, N., Akechi, T., Inagaki, M., Asai, M., Goto, K., ... Uchitomi, Y. (2008). Marital status and non-small cell lung cancer survival: The Lung Cancer Database Project in Japan. Psycho-Oncology, 17(9), 869-876. https://doi.org/10.1002/pon.1296

Marital status and non-small cell lung cancer survival : The Lung Cancer Database Project in Japan. / Saito-Nakaya, Kumi; Nakaya, Naoki; Akechi, Tatsuo; Inagaki, Masatoshi; Asai, Mariko; Goto, Koichi; Nagai, Kanji; Nishiwaki, Yutaka; Tsugane, Shoichiro; Fukudo, Shin; Uchitomi, Yosuke.

In: Psycho-Oncology, Vol. 17, No. 9, 09.2008, p. 869-876.

Research output: Contribution to journalArticle

Saito-Nakaya, K, Nakaya, N, Akechi, T, Inagaki, M, Asai, M, Goto, K, Nagai, K, Nishiwaki, Y, Tsugane, S, Fukudo, S & Uchitomi, Y 2008, 'Marital status and non-small cell lung cancer survival: The Lung Cancer Database Project in Japan', Psycho-Oncology, vol. 17, no. 9, pp. 869-876. https://doi.org/10.1002/pon.1296
Saito-Nakaya K, Nakaya N, Akechi T, Inagaki M, Asai M, Goto K et al. Marital status and non-small cell lung cancer survival: The Lung Cancer Database Project in Japan. Psycho-Oncology. 2008 Sep;17(9):869-876. https://doi.org/10.1002/pon.1296
Saito-Nakaya, Kumi ; Nakaya, Naoki ; Akechi, Tatsuo ; Inagaki, Masatoshi ; Asai, Mariko ; Goto, Koichi ; Nagai, Kanji ; Nishiwaki, Yutaka ; Tsugane, Shoichiro ; Fukudo, Shin ; Uchitomi, Yosuke. / Marital status and non-small cell lung cancer survival : The Lung Cancer Database Project in Japan. In: Psycho-Oncology. 2008 ; Vol. 17, No. 9. pp. 869-876.
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