Marine cytotoxic macrolides haterumalides and biselides, and related natural products

Hideo Kigoshi, Ichiro Hayakawa

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Marine animals and plants are rich sources of bioactive natural products. Haterumalides and biselides, isolated from Okinawan marine animals, are 14-membered macrolides with strong cytotoxicity against human cancer cell lines. This review highlights the isolation, structures, bioactivities, and total synthesis of haterumalides, biselides, and related natural products.

Original languageEnglish
Pages (from-to)254-264
Number of pages11
JournalChemical Record
Volume7
Issue number4
DOIs
Publication statusPublished - 2007
Externally publishedYes

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Macrolides
Biological Products
Animals
Cytotoxicity
Bioactivity
Cells
Cell Line
Neoplasms

Keywords

  • Biselides
  • Haterumalides
  • Human cancer cell lines
  • Marine cytotoxic macrolide

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Marine cytotoxic macrolides haterumalides and biselides, and related natural products. / Kigoshi, Hideo; Hayakawa, Ichiro.

In: Chemical Record, Vol. 7, No. 4, 2007, p. 254-264.

Research output: Contribution to journalArticle

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