Abstract
Marine animals and plants are rich sources of bioactive natural products. Haterumalides and biselides, isolated from Okinawan marine animals, are 14-membered macrolides with strong cytotoxicity against human cancer cell lines. This review highlights the isolation, structures, bioactivities, and total synthesis of haterumalides, biselides, and related natural products.
| Original language | English |
|---|---|
| Pages (from-to) | 254-264 |
| Number of pages | 11 |
| Journal | Chemical Record |
| Volume | 7 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - Oct 4 2007 |
| Externally published | Yes |
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Keywords
- Biselides
- Haterumalides
- Human cancer cell lines
- Marine cytotoxic macrolide
ASJC Scopus subject areas
- Chemistry(all)
- Biochemistry
- Chemical Engineering(all)
- Materials Chemistry
Cite this
Kigoshi, H., & Hayakawa, I. (2007). Marine cytotoxic macrolides haterumalides and biselides, and related natural products. Chemical Record, 7(4), 254-264. https://doi.org/10.1002/tcr.20119