Manifestation of central diabetes insipidus in a patient with thyroid storm

Akiko Nakamichi, Kazuki Ocho, Kosuke Oka, Miho Yasuda, Kou Hasegawa, Masaya Iwamuro, Mikako Obika, Kanmei Rai, Fumio Otsuka

Research output: Contribution to journalArticle

Abstract

We herein report a case of central diabetes insipidus complicated with thyroid storm. A middle-aged woman who was receiving treatment for Graves’ disease suddenly complained of polydipsia, polyuria and general fatigue. Laboratory tests showed hyperthyroidism, hypernatremia, hypoosmolar urine and a decreased plasma vasopressin level. The occurrence of central diabetes insipidus with hyperthyroidism was revealed on the basis of pituitary magnetic resonance imaging, a water deprivation test and a desmopressin test. The clinical co-existence of diabetes insipidus and hyperthyroidism is very rare; however, the complication should be considered when hypernatremia and/or dehydration progress in patients with Graves’s disease as a common autoimmune-related etiology.

Original languageEnglish
Pages (from-to)1939-1942
Number of pages4
JournalInternal Medicine
Volume57
Issue number13
DOIs
Publication statusPublished - Jan 1 2018

Fingerprint

Thyroid Crisis
Neurogenic Diabetes Insipidus
Hyperthyroidism
Hypernatremia
Polydipsia
Water Deprivation
Polyuria
Deamino Arginine Vasopressin
Diabetes Insipidus
Graves Disease
Vasopressins
Dehydration
Fatigue
Magnetic Resonance Imaging
Urine
Therapeutics

Keywords

  • Central diabetes insipidus
  • Graves’ disease
  • Hyperthyroidism
  • Lymphocytic infundibulo-neurohypophysitis and thyroid crisis

ASJC Scopus subject areas

  • Internal Medicine

Cite this

Manifestation of central diabetes insipidus in a patient with thyroid storm. / Nakamichi, Akiko; Ocho, Kazuki; Oka, Kosuke; Yasuda, Miho; Hasegawa, Kou; Iwamuro, Masaya; Obika, Mikako; Rai, Kanmei; Otsuka, Fumio.

In: Internal Medicine, Vol. 57, No. 13, 01.01.2018, p. 1939-1942.

Research output: Contribution to journalArticle

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