Manganese-catalyzed insertion of aldehydes into a C-H bond

Yoichiro Kuninobu, Yuta Nishina, Takahiro Takeuchi, Kazuhiko Takai

Research output: Contribution to journalArticle

155 Citations (Scopus)

Abstract

(Chemical Equation Presented) Mn gets in the game: In the presence of a manganese catalyst and a stoichiometric amount of hydrosilane, aldehydes insert into C-H bonds of aromatic rings of compounds with directing groups (see scheme). This first example of a manganese-catalyzed chemical transformation through C-H bond activation gives silyl ethers in good to excellent yields and can also be applied to asymmetric transformation.

Original languageEnglish
Pages (from-to)6518-6520
Number of pages3
JournalAngewandte Chemie - International Edition
Volume46
Issue number34
DOIs
Publication statusPublished - 2007

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Keywords

  • Aldehydes
  • Asymmetric synthesis
  • C-H activation
  • Manganese
  • Silyl ethers

ASJC Scopus subject areas

  • Chemistry(all)

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