TY - JOUR
T1 - Malignant cerebellar astrocytoma developing 15 years after radiation therapy for a medulloblastoma
AU - Furuta, T.
AU - Sugiu, K.
AU - Tamiya, T.
AU - Matsumoto, K.
AU - Ohmoto, T.
PY - 1998/3
Y1 - 1998/3
N2 - A case of malignant cerebellar astrocytoma occurring 15 years after the radiation therapy for a medulloblastoma is reported. The tumor developed at the same site of irradiation after a sufficient latent period and was completely different from medulloblastoma in its histology. This tumor fulfilled the criteria of radiation-induced neoplasm. Only seven similar cases have been reported up to the present. Whole neuraxis irradiation following a gross total resection is a standard treatment for medulloblastoma, but the possibility of the development of radiation-induced tumors must be borne in mind for a long time after the radiation therapy for medulloblastoma.
AB - A case of malignant cerebellar astrocytoma occurring 15 years after the radiation therapy for a medulloblastoma is reported. The tumor developed at the same site of irradiation after a sufficient latent period and was completely different from medulloblastoma in its histology. This tumor fulfilled the criteria of radiation-induced neoplasm. Only seven similar cases have been reported up to the present. Whole neuraxis irradiation following a gross total resection is a standard treatment for medulloblastoma, but the possibility of the development of radiation-induced tumors must be borne in mind for a long time after the radiation therapy for medulloblastoma.
KW - Malignant astrocytoma
KW - Medulloblastoma
KW - Radiation therapy
KW - Radiation-induced tumor
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U2 - 10.1016/S0303-8467(97)00122-4
DO - 10.1016/S0303-8467(97)00122-4
M3 - Article
C2 - 9637208
AN - SCOPUS:0031835667
SN - 0303-8467
VL - 100
SP - 56
EP - 59
JO - Clinical Neurology and Neurosurgery
JF - Clinical Neurology and Neurosurgery
IS - 1
ER -