Magnetic Attachment of Lipase Immobilized on Bacteriogenic Iron Oxide Inside a Microtube Reactor for the Kinetic Resolution of Secondary Alcohols

Kyoko Mandai, Takehiro Fukuda, Yuki Miyazaki, Hideki Hashimoto, Hiroki Mandai, Tadashi Ema, Jun Takada, Seiji Suga

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

A PTFE microtube reactor was constructed with lipase immobilized on magnetized bacteriogenic iron oxide, which was retained inside of the tube by attraction to an external magnet. The reactor was used for the lipase-promoted kinetic resolution of secondary alcohols and gave sufficient catalytic activity, which was maintained during long-term flow over 14 days.

Original languageEnglish
Pages (from-to)805-810
Number of pages6
JournalSynlett
Volume28
Issue number7
DOIs
Publication statusPublished - Apr 21 2017

Keywords

  • iron oxide
  • kinetic resolution
  • lipase
  • magnetic attachment
  • microreactor

ASJC Scopus subject areas

  • Organic Chemistry

Fingerprint Dive into the research topics of 'Magnetic Attachment of Lipase Immobilized on Bacteriogenic Iron Oxide Inside a Microtube Reactor for the Kinetic Resolution of Secondary Alcohols'. Together they form a unique fingerprint.

  • Cite this