Lymphatic endothelium expresses PECAM-1

Yoshihiko Sawa, Shigemitsu Yoshida, Yuichi Ashikaga, Takenori Kim, Yuji Yamaoka, Hiroshi Shiroto

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

The expression of adhesion molecules on the lymphatic endothelium of human small intestine and submandibular lymph node was studied immunohistochemically with the antibodies for selectin family and Ig supefamily members. In both small intestine and submandibular lymph node, lymphatic endothelium did not express intercellular adhesion molecule-1 and endothelial cell-selectin but expressed platelet-endothelial cell adhesion molecule-1 (PECAM-1). Though lymphatic vessels may not have a positive function in leukocyte rolling and adhesion, lymphatic endothelium may interact with leukocytes, with PECAM-1 playing a role.

Original languageEnglish
Pages (from-to)377-382
Number of pages6
JournalTissue and Cell
Volume30
Issue number3
DOIs
Publication statusPublished - 1998

Keywords

  • Adhesion molecule
  • Antibody
  • Immunohistochemistry
  • Lymphatic vessel
  • PECAM-1

ASJC Scopus subject areas

  • Developmental Biology
  • Cell Biology

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    Sawa, Y., Yoshida, S., Ashikaga, Y., Kim, T., Yamaoka, Y., & Shiroto, H. (1998). Lymphatic endothelium expresses PECAM-1. Tissue and Cell, 30(3), 377-382. https://doi.org/10.1016/S0040-8166(98)80051-7