Lymphadenoid Structure Induced by Gold Hypersensitivity

Keiji Iwatsuki, Hachiro Tagami, Takahiko Moriguchi, Mizuho Yamada

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

An allergic sensitivity to gold earrings produced a lymphadenoid reaction with germinal centers in the dermis of the pierced earlobes of a 21-year-old woman. However, a patch test for 1% gold sodium thiomalate gave a long-lasting, clinically and histologically eczematous response. Electron microscopic and cytochemical observations showed that non-T lymphocytes and plasma cells were dominant in the dermal infiltrate of the lesions, whereas lymphocytes with convoluted nuclei (which were probably T cells) and monocytes invaded the epidermis in the patch test site. These findings suggest that continuous exposure of the dermis to gold in a sensitized person may induce a lymphadenoid cellular reaction different from the histologic findings seen after contact with the epidermis.

Original languageEnglish
Pages (from-to)608-611
Number of pages4
JournalArchives of Dermatology
Volume118
Issue number8
DOIs
Publication statusPublished - 1982
Externally publishedYes

Fingerprint

Patch Tests
Dermis
Epidermis
Gold
Hypersensitivity
Gold Sodium Thiomalate
Lymphocytes
Germinal Center
Plasma Cells
Monocytes
Electrons
T-Lymphocytes
Skin

ASJC Scopus subject areas

  • Dermatology

Cite this

Lymphadenoid Structure Induced by Gold Hypersensitivity. / Iwatsuki, Keiji; Tagami, Hachiro; Moriguchi, Takahiko; Yamada, Mizuho.

In: Archives of Dermatology, Vol. 118, No. 8, 1982, p. 608-611.

Research output: Contribution to journalArticle

Iwatsuki, K, Tagami, H, Moriguchi, T & Yamada, M 1982, 'Lymphadenoid Structure Induced by Gold Hypersensitivity', Archives of Dermatology, vol. 118, no. 8, pp. 608-611. https://doi.org/10.1001/archderm.1982.01650200076023
Iwatsuki, Keiji ; Tagami, Hachiro ; Moriguchi, Takahiko ; Yamada, Mizuho. / Lymphadenoid Structure Induced by Gold Hypersensitivity. In: Archives of Dermatology. 1982 ; Vol. 118, No. 8. pp. 608-611.
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