Abstract
An allergic sensitivity to gold earrings produced a lymphadenoid reaction with germinal centers in the dermis of the pierced earlobes of a 21-year-old woman. However, a patch test for 1% gold sodium thiomalate gave a long-lasting, clinically and histologically eczematous response. Electron microscopic and cytochemical observations showed that non-T lymphocytes and plasma cells were dominant in the dermal infiltrate of the lesions, whereas lymphocytes with convoluted nuclei (which were probably T cells) and monocytes invaded the epidermis in the patch test site. These findings suggest that continuous exposure of the dermis to gold in a sensitized person may induce a lymphadenoid cellular reaction different from the histologic findings seen after contact with the epidermis.
| Original language | English |
|---|---|
| Pages (from-to) | 608-611 |
| Number of pages | 4 |
| Journal | Archives of Dermatology |
| Volume | 118 |
| Issue number | 8 |
| DOIs | |
| Publication status | Published - 1982 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Dermatology
Cite this
Lymphadenoid Structure Induced by Gold Hypersensitivity. / Iwatsuki, Keiji; Tagami, Hachiro; Moriguchi, Takahiko; Yamada, Mizuho.
In: Archives of Dermatology, Vol. 118, No. 8, 1982, p. 608-611.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Lymphadenoid Structure Induced by Gold Hypersensitivity
AU - Iwatsuki, Keiji
AU - Tagami, Hachiro
AU - Moriguchi, Takahiko
AU - Yamada, Mizuho
PY - 1982
Y1 - 1982
N2 - An allergic sensitivity to gold earrings produced a lymphadenoid reaction with germinal centers in the dermis of the pierced earlobes of a 21-year-old woman. However, a patch test for 1% gold sodium thiomalate gave a long-lasting, clinically and histologically eczematous response. Electron microscopic and cytochemical observations showed that non-T lymphocytes and plasma cells were dominant in the dermal infiltrate of the lesions, whereas lymphocytes with convoluted nuclei (which were probably T cells) and monocytes invaded the epidermis in the patch test site. These findings suggest that continuous exposure of the dermis to gold in a sensitized person may induce a lymphadenoid cellular reaction different from the histologic findings seen after contact with the epidermis.
AB - An allergic sensitivity to gold earrings produced a lymphadenoid reaction with germinal centers in the dermis of the pierced earlobes of a 21-year-old woman. However, a patch test for 1% gold sodium thiomalate gave a long-lasting, clinically and histologically eczematous response. Electron microscopic and cytochemical observations showed that non-T lymphocytes and plasma cells were dominant in the dermal infiltrate of the lesions, whereas lymphocytes with convoluted nuclei (which were probably T cells) and monocytes invaded the epidermis in the patch test site. These findings suggest that continuous exposure of the dermis to gold in a sensitized person may induce a lymphadenoid cellular reaction different from the histologic findings seen after contact with the epidermis.
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U2 - 10.1001/archderm.1982.01650200076023
DO - 10.1001/archderm.1982.01650200076023
M3 - Article
C2 - 7103532
AN - SCOPUS:0020050776
VL - 118
SP - 608
EP - 611
JO - JAMA Dermatology
JF - JAMA Dermatology
SN - 2168-6068
IS - 8
ER -