Luteal Prostaglandin F: New Concepts of Prostaglandin F Secretion and Its Actions within the Bovine Corpus Luteum - Review

K. Okuda, D. J. Skarzynski

Research output: Contribution to journalReview articlepeer-review

5 Citations (Scopus)


The corpus luteum (CL) is a temporary endocrine gland whose main function is to secrete progesterone to support pregnancy. On the other hand, the cyclic bovine CL has also been shown to be a site of prostaglandin F (PGF) production. Although there is general agreement that endometrial PGF is an essential luteolysin in cattle, luteal PGF seems to play a luteotropic role as an autocrine and/or paracrine factor, especially for the development and maintenance of the CL. This supposition is based on evidence that some of the prerequisites for autocrine/paracrine mechanisms are present, including local production of PGF and the existence of specific binding sites within the CL. The purpose of this paper is to review the regulation of luteal PGF secretion, its action on CL as an autocrine and/or paracrine factor and the receptivity of bovine CL to. PGF.

Original languageEnglish
Pages (from-to)390-400
Number of pages11
JournalAsian-Australasian Journal of Animal Sciences
Issue number3
Publication statusPublished - Mar 2000


  • Corpus Luteum
  • Cow
  • Luteolysis
  • PGF
  • PGF Receptor

ASJC Scopus subject areas

  • Food Science
  • Animal Science and Zoology
  • Engineering(all)


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