The corpus luteum (CL) is a temporary endocrine gland whose main function is to secrete progesterone to support pregnancy. On the other hand, the cyclic bovine CL has also been shown to be a site of prostaglandin F2α (PGF2α) production. Although there is general agreement that endometrial PGF2α is an essential luteolysin in cattle, luteal PGF2α seems to play a luteotropic role as an autocrine and/or paracrine factor, especially for the development and maintenance of the CL. This supposition is based on evidence that some of the prerequisites for autocrine/paracrine mechanisms are present, including local production of PGF2α and the existence of specific binding sites within the CL. The purpose of this paper is to review the regulation of luteal PGF2α secretion, its action on CL as an autocrine and/or paracrine factor and the receptivity of bovine CL to. PGF2α.
|Number of pages||11|
|Journal||Asian-Australasian Journal of Animal Sciences|
|Publication status||Published - Mar 2000|
- Corpus Luteum
- PGF Receptor
ASJC Scopus subject areas
- Animal Science and Zoology