Lung transplantation in rats

Tomohiro Kawamura, Yugo Tanaka, Norihisa Shigemura, Yoshiya Toyoda, Atsunori Nakao

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)

Abstract

This chapter describes a unilateral, orthotopic lung transplantation (LTx) model using the cuff technique in rats. The advantage of this model over the suture technique includes a decrease in operation time, prevention of bleeding from the vascular anastomosis site, and shorter training period with stable outcomes. The rat LTx model has been proven valid for understanding physiological/pathological events occurring in lung grafts, as well as evaluating graft injuries due to inflammation or rejection, as seen in clinical lung transplant.& copy 2013 Nova Science Publishers, Inc.

Original languageEnglish
Title of host publicationExperimental Organ Transplantation
PublisherNova Science Publishers, Inc.
Pages159-173
Number of pages15
ISBN (Print)9781624179495
Publication statusPublished - Dec 1 2013
Externally publishedYes

Keywords

  • Allograft rejection
  • Cuff technique
  • Ischemia/reperfusion injury
  • Non-suturing anastomosis
  • Orthotopic rat lung transplantation

ASJC Scopus subject areas

  • Medicine(all)

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  • Cite this

    Kawamura, T., Tanaka, Y., Shigemura, N., Toyoda, Y., & Nakao, A. (2013). Lung transplantation in rats. In Experimental Organ Transplantation (pp. 159-173). Nova Science Publishers, Inc..