Lung function and blood markers of nutritional status in non-COPD aging men with smoking history: a cross-sectional study.

Nobuyoshi Shiozawa, Kanae Hayashimoto, Etsuji Suzuki, Hiroshi Kikuchi, Shingo Takata, Kozo Ashida, Masutaka Watanabe, Yasuhiro Hosaki, Fumihiro Mitsunobu

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Cigarette smoking and advanced age are well known as risk factors for chronic obstructive pulmonary disease (COPD), and nutritional abnormalities are important in patients with COPD. However, little is known about the nutritional status in non-COPD aging men with smoking history. We therefore investigated whether reduced lung function is associated with lower blood markers of nutritional status in those men. This association was examined in a cross-sectional study of 65 Japanese male current or former smokers aged 50 to 80 years: 48 without COPD (non-COPD group), divided into tertiles according to forced expiratory volume in one second as percent of forced vital capacity (FEV(1)/FVC), and 17 with COPD (COPD group). After adjustment for potential confounders, lower FEV(1)/FVC was significantly associated with lower red blood cell count (RBCc), hemoglobin, and total protein (TP); not with total energy intake. The difference in adjusted RBCc and TP among the non-COPD group tertiles was greater than that between the bottom tertile in the non-COPD group and the COPD group. In non-COPD aging men with smoking history, trends toward reduced nutritional status and anemia may independently emerge in blood components along with decreased lung function even before COPD onset.

Original languageEnglish
Pages (from-to)233-240
Number of pages8
JournalInternational journal of chronic obstructive pulmonary disease
Volume5
Publication statusPublished - 2010
Externally publishedYes

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Health Policy
  • Public Health, Environmental and Occupational Health

Fingerprint Dive into the research topics of 'Lung function and blood markers of nutritional status in non-COPD aging men with smoking history: a cross-sectional study.'. Together they form a unique fingerprint.

  • Cite this