Lung function and blood markers of nutritional status in non-COPD aging men with smoking history

a cross-sectional study.

Nobuyoshi Shiozawa, Kanae Hayashimoto, Etsuji Suzuki, Hiroshi Kikuchi, Shingo Takata, Kozo Ashida, Masutaka Watanabe, Yasuhiro Hosaki, Fumihiro Mitsunobu

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Cigarette smoking and advanced age are well known as risk factors for chronic obstructive pulmonary disease (COPD), and nutritional abnormalities are important in patients with COPD. However, little is known about the nutritional status in non-COPD aging men with smoking history. We therefore investigated whether reduced lung function is associated with lower blood markers of nutritional status in those men. This association was examined in a cross-sectional study of 65 Japanese male current or former smokers aged 50 to 80 years: 48 without COPD (non-COPD group), divided into tertiles according to forced expiratory volume in one second as percent of forced vital capacity (FEV(1)/FVC), and 17 with COPD (COPD group). After adjustment for potential confounders, lower FEV(1)/FVC was significantly associated with lower red blood cell count (RBCc), hemoglobin, and total protein (TP); not with total energy intake. The difference in adjusted RBCc and TP among the non-COPD group tertiles was greater than that between the bottom tertile in the non-COPD group and the COPD group. In non-COPD aging men with smoking history, trends toward reduced nutritional status and anemia may independently emerge in blood components along with decreased lung function even before COPD onset.

Original languageEnglish
Pages (from-to)233-240
Number of pages8
JournalInternational journal of chronic obstructive pulmonary disease
Volume5
Publication statusPublished - 2010
Externally publishedYes

Fingerprint

Obstructive Lung Diseases
Nutritional Status
Chronic Obstructive Pulmonary Disease
Cross-Sectional Studies
Smoking
History
Lung
Erythrocyte Count
Vital Capacity
Forced Expiratory Volume
Energy Intake
Anemia
Hemoglobins
Proteins

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Lung function and blood markers of nutritional status in non-COPD aging men with smoking history : a cross-sectional study. / Shiozawa, Nobuyoshi; Hayashimoto, Kanae; Suzuki, Etsuji; Kikuchi, Hiroshi; Takata, Shingo; Ashida, Kozo; Watanabe, Masutaka; Hosaki, Yasuhiro; Mitsunobu, Fumihiro.

In: International journal of chronic obstructive pulmonary disease, Vol. 5, 2010, p. 233-240.

Research output: Contribution to journalArticle

@article{e694bcf1b124449ea57e8ce9eee2d704,
title = "Lung function and blood markers of nutritional status in non-COPD aging men with smoking history: a cross-sectional study.",
abstract = "Cigarette smoking and advanced age are well known as risk factors for chronic obstructive pulmonary disease (COPD), and nutritional abnormalities are important in patients with COPD. However, little is known about the nutritional status in non-COPD aging men with smoking history. We therefore investigated whether reduced lung function is associated with lower blood markers of nutritional status in those men. This association was examined in a cross-sectional study of 65 Japanese male current or former smokers aged 50 to 80 years: 48 without COPD (non-COPD group), divided into tertiles according to forced expiratory volume in one second as percent of forced vital capacity (FEV(1)/FVC), and 17 with COPD (COPD group). After adjustment for potential confounders, lower FEV(1)/FVC was significantly associated with lower red blood cell count (RBCc), hemoglobin, and total protein (TP); not with total energy intake. The difference in adjusted RBCc and TP among the non-COPD group tertiles was greater than that between the bottom tertile in the non-COPD group and the COPD group. In non-COPD aging men with smoking history, trends toward reduced nutritional status and anemia may independently emerge in blood components along with decreased lung function even before COPD onset.",
author = "Nobuyoshi Shiozawa and Kanae Hayashimoto and Etsuji Suzuki and Hiroshi Kikuchi and Shingo Takata and Kozo Ashida and Masutaka Watanabe and Yasuhiro Hosaki and Fumihiro Mitsunobu",
year = "2010",
language = "English",
volume = "5",
pages = "233--240",
journal = "International Journal of COPD",
issn = "1176-9106",
publisher = "Dove Medical Press Ltd.",

}

TY - JOUR

T1 - Lung function and blood markers of nutritional status in non-COPD aging men with smoking history

T2 - a cross-sectional study.

AU - Shiozawa, Nobuyoshi

AU - Hayashimoto, Kanae

AU - Suzuki, Etsuji

AU - Kikuchi, Hiroshi

AU - Takata, Shingo

AU - Ashida, Kozo

AU - Watanabe, Masutaka

AU - Hosaki, Yasuhiro

AU - Mitsunobu, Fumihiro

PY - 2010

Y1 - 2010

N2 - Cigarette smoking and advanced age are well known as risk factors for chronic obstructive pulmonary disease (COPD), and nutritional abnormalities are important in patients with COPD. However, little is known about the nutritional status in non-COPD aging men with smoking history. We therefore investigated whether reduced lung function is associated with lower blood markers of nutritional status in those men. This association was examined in a cross-sectional study of 65 Japanese male current or former smokers aged 50 to 80 years: 48 without COPD (non-COPD group), divided into tertiles according to forced expiratory volume in one second as percent of forced vital capacity (FEV(1)/FVC), and 17 with COPD (COPD group). After adjustment for potential confounders, lower FEV(1)/FVC was significantly associated with lower red blood cell count (RBCc), hemoglobin, and total protein (TP); not with total energy intake. The difference in adjusted RBCc and TP among the non-COPD group tertiles was greater than that between the bottom tertile in the non-COPD group and the COPD group. In non-COPD aging men with smoking history, trends toward reduced nutritional status and anemia may independently emerge in blood components along with decreased lung function even before COPD onset.

AB - Cigarette smoking and advanced age are well known as risk factors for chronic obstructive pulmonary disease (COPD), and nutritional abnormalities are important in patients with COPD. However, little is known about the nutritional status in non-COPD aging men with smoking history. We therefore investigated whether reduced lung function is associated with lower blood markers of nutritional status in those men. This association was examined in a cross-sectional study of 65 Japanese male current or former smokers aged 50 to 80 years: 48 without COPD (non-COPD group), divided into tertiles according to forced expiratory volume in one second as percent of forced vital capacity (FEV(1)/FVC), and 17 with COPD (COPD group). After adjustment for potential confounders, lower FEV(1)/FVC was significantly associated with lower red blood cell count (RBCc), hemoglobin, and total protein (TP); not with total energy intake. The difference in adjusted RBCc and TP among the non-COPD group tertiles was greater than that between the bottom tertile in the non-COPD group and the COPD group. In non-COPD aging men with smoking history, trends toward reduced nutritional status and anemia may independently emerge in blood components along with decreased lung function even before COPD onset.

UR - http://www.scopus.com/inward/record.url?scp=79952022047&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=79952022047&partnerID=8YFLogxK

M3 - Article

VL - 5

SP - 233

EP - 240

JO - International Journal of COPD

JF - International Journal of COPD

SN - 1176-9106

ER -