Lumped parameter model for hemodynamic simulation of congenital heart diseases

Shuji Shimizu, Dai Une, Toru Kawada, Yohsuke Hayama, Atsunori Kamiya, Toshiaki Shishido, Masaru Sugimachi

Research output: Contribution to journalReview article

7 Citations (Scopus)

Abstract

The recent development of computer technology has made it possible to simulate the hemodynamics of congenital heart diseases on a desktop computer. However, multi-scale modeling of the cardiovascular system based on computed tomographic and magnetic resonance images still requires long simulation times. The lumped parameter model is potentially beneficial for real-time bedside simulation of congenital heart diseases. In this review, we introduce the basics of the lumped parameter model (time-varying elastance chamber model combined with modified Windkessel vasculature model) and illustrate its usage in hemodynamic simulation of congenital heart diseases using examples such as hypoplastic left heart syndrome and Fontan circulation. We also discuss the advantages of the lumped parameter model and the problems for clinical use.

Original languageEnglish
Pages (from-to)103-111
Number of pages9
JournalJournal of Physiological Sciences
Volume68
Issue number2
DOIs
Publication statusPublished - Mar 1 2018

Keywords

  • Congenital heart diseases
  • Hemodynamic simulation
  • Lumped parameter model
  • Time-varying elastance
  • Windkessel model

ASJC Scopus subject areas

  • Physiology

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