Luminal acidification of diverse organelles by V-ATPase in animal cells

Masamitsu Futai, Toshihiko Oka, Ge Hong Sun-Wada, Yoshinori Moriyama, Hiroshi Kanazawa, Yoh Wada

Research output: Contribution to journalArticle

121 Citations (Scopus)

Abstract

Eukaryotic cells contain organelles bounded by a single membrane in the cytoplasm. These organelles have differentiated to carry out various functions in the pathways of endocytosis and exocytosis. Their lumina are acidic, with pH ranging from 4.5 to 6.5. This-article describes recent studies on these animal cell organelles focusing on (1) the primary ... proton pump (vacuolar-type H+-ATPase) and (2) the functions of the organelle luminal acidity, we also discuss similarities and differences between vacuolar-type H+-ATPase and F-type ATPase. Our own studies and interests are emphasized.

Original languageEnglish
Pages (from-to)107-116
Number of pages10
JournalJournal of Experimental Biology
Volume203
Issue number1
Publication statusPublished - Jan 2000
Externally publishedYes

Fingerprint

cell organelle
H-transporting ATP synthase
Organelles
acidification
organelles
Adenosine Triphosphatases
Vacuolar Proton-Translocating ATPases
animal
cytoplasm
acidity
animals
pump
cells
membrane
Proton Pumps
proton pump
exocytosis
Exocytosis
endocytosis
Eukaryotic Cells

Keywords

  • ATPase
  • Endomembrane organelle
  • Organelle
  • Proton pump
  • V-ATPase
  • Vacuolar-type ATPase

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Agricultural and Biological Sciences (miscellaneous)

Cite this

Futai, M., Oka, T., Sun-Wada, G. H., Moriyama, Y., Kanazawa, H., & Wada, Y. (2000). Luminal acidification of diverse organelles by V-ATPase in animal cells. Journal of Experimental Biology, 203(1), 107-116.

Luminal acidification of diverse organelles by V-ATPase in animal cells. / Futai, Masamitsu; Oka, Toshihiko; Sun-Wada, Ge Hong; Moriyama, Yoshinori; Kanazawa, Hiroshi; Wada, Yoh.

In: Journal of Experimental Biology, Vol. 203, No. 1, 01.2000, p. 107-116.

Research output: Contribution to journalArticle

Futai, M, Oka, T, Sun-Wada, GH, Moriyama, Y, Kanazawa, H & Wada, Y 2000, 'Luminal acidification of diverse organelles by V-ATPase in animal cells', Journal of Experimental Biology, vol. 203, no. 1, pp. 107-116.
Futai M, Oka T, Sun-Wada GH, Moriyama Y, Kanazawa H, Wada Y. Luminal acidification of diverse organelles by V-ATPase in animal cells. Journal of Experimental Biology. 2000 Jan;203(1):107-116.
Futai, Masamitsu ; Oka, Toshihiko ; Sun-Wada, Ge Hong ; Moriyama, Yoshinori ; Kanazawa, Hiroshi ; Wada, Yoh. / Luminal acidification of diverse organelles by V-ATPase in animal cells. In: Journal of Experimental Biology. 2000 ; Vol. 203, No. 1. pp. 107-116.
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