Luminal acidification of diverse organelles by V-ATPase in animal cells

Masamitsu Futai; Toshihiko Oka; Ge Hong Sun-Wada; Yoshinori Moriyama; Hiroshi Kanazawa; Yoh Wada

Luminal acidification of diverse organelles by V-ATPase in animal cells

Masamitsu Futai, Toshihiko Oka, Ge Hong Sun-Wada, Yoshinori Moriyama, Hiroshi Kanazawa, Yoh Wada

Research output: Contribution to journal › Article › peer-review

Abstract

Eukaryotic cells contain organelles bounded by a single membrane in the cytoplasm. These organelles have differentiated to carry out various functions in the pathways of endocytosis and exocytosis. Their lumina are acidic, with pH ranging from 4.5 to 6.5. This-article describes recent studies on these animal cell organelles focusing on (1) the primary ... proton pump (vacuolar-type H⁺-ATPase) and (2) the functions of the organelle luminal acidity, we also discuss similarities and differences between vacuolar-type H⁺-ATPase and F-type ATPase. Our own studies and interests are emphasized.

Original language	English
Pages (from-to)	107-116
Number of pages	10
Journal	Journal of Experimental Biology
Volume	203
Issue number	1
Publication status	Published - Jan 2000
Externally published	Yes

Keywords

ATPase
Endomembrane organelle
Organelle
Proton pump
V-ATPase
Vacuolar-type ATPase

ASJC Scopus subject areas

Ecology, Evolution, Behavior and Systematics
Physiology
Aquatic Science
Animal Science and Zoology
Molecular Biology
Insect Science

Cite this

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abstract = "Eukaryotic cells contain organelles bounded by a single membrane in the cytoplasm. These organelles have differentiated to carry out various functions in the pathways of endocytosis and exocytosis. Their lumina are acidic, with pH ranging from 4.5 to 6.5. This-article describes recent studies on these animal cell organelles focusing on (1) the primary ... proton pump (vacuolar-type H+-ATPase) and (2) the functions of the organelle luminal acidity, we also discuss similarities and differences between vacuolar-type H+-ATPase and F-type ATPase. Our own studies and interests are emphasized.",

keywords = "ATPase, Endomembrane organelle, Organelle, Proton pump, V-ATPase, Vacuolar-type ATPase",

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AU - Futai, Masamitsu

AU - Oka, Toshihiko

AU - Sun-Wada, Ge Hong

AU - Moriyama, Yoshinori

AU - Kanazawa, Hiroshi

AU - Wada, Yoh

PY - 2000/1

Y1 - 2000/1

N2 - Eukaryotic cells contain organelles bounded by a single membrane in the cytoplasm. These organelles have differentiated to carry out various functions in the pathways of endocytosis and exocytosis. Their lumina are acidic, with pH ranging from 4.5 to 6.5. This-article describes recent studies on these animal cell organelles focusing on (1) the primary ... proton pump (vacuolar-type H+-ATPase) and (2) the functions of the organelle luminal acidity, we also discuss similarities and differences between vacuolar-type H+-ATPase and F-type ATPase. Our own studies and interests are emphasized.

AB - Eukaryotic cells contain organelles bounded by a single membrane in the cytoplasm. These organelles have differentiated to carry out various functions in the pathways of endocytosis and exocytosis. Their lumina are acidic, with pH ranging from 4.5 to 6.5. This-article describes recent studies on these animal cell organelles focusing on (1) the primary ... proton pump (vacuolar-type H+-ATPase) and (2) the functions of the organelle luminal acidity, we also discuss similarities and differences between vacuolar-type H+-ATPase and F-type ATPase. Our own studies and interests are emphasized.

KW - ATPase

KW - Endomembrane organelle

KW - Organelle

KW - Proton pump

KW - V-ATPase

KW - Vacuolar-type ATPase

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Luminal acidification of diverse organelles by V-ATPase in animal cells

Abstract

Keywords

ASJC Scopus subject areas

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