Lowe syndrome oral findings: Case report

Rena Okawa, Shuhei Naka, Kanae Saga, Kazuhiko Nakano

Research output: Contribution to journalArticle

Abstract

Lowe syndrome is an X-linked recessive disorder characterized by anomalies of the eye, nervous system, and kidney, and caused by a mutation of the oculocerebrorenal gene (OCRL1) on the X-chromosome. Dental manifestations are associated with rickets due to renal dysfunction. A 2-year-1-month-old boy with Lowe syndrome came to our clinic for consultation in regard to mobility of the primary mandibular incisors. Periapical radiograph findings showed alveolar bone absorption and a wide pulp chamber. Dental caries extending to the pulp was detected on the palatal side of the maxillary central incisors. We initially provided brushing and dietary habit instructions, and subsequently performed periodontal and dental caries treatments. Repeated periodontal therapy led to disappearance of mobility of the affected teeth at the age of 3Y3M.

Original languageEnglish
Pages (from-to)34-37
Number of pages4
JournalPediatric Dental Journal
Volume26
Issue number1
DOIs
Publication statusPublished - Apr 1 2016
Externally publishedYes

Fingerprint

Oculocerebrorenal Syndrome
Dental Caries
Incisor
Tooth Mobility
Nervous System Malformations
Kidney
Rickets
Dental Pulp Cavity
X Chromosome
Feeding Behavior
Tooth
Referral and Consultation
Bone and Bones
Mutation
Therapeutics
Genes

Keywords

  • Lowe syndrome
  • Mobility of primary incisors
  • Rickets

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Dentistry (miscellaneous)

Cite this

Lowe syndrome oral findings : Case report. / Okawa, Rena; Naka, Shuhei; Saga, Kanae; Nakano, Kazuhiko.

In: Pediatric Dental Journal, Vol. 26, No. 1, 01.04.2016, p. 34-37.

Research output: Contribution to journalArticle

Okawa, Rena ; Naka, Shuhei ; Saga, Kanae ; Nakano, Kazuhiko. / Lowe syndrome oral findings : Case report. In: Pediatric Dental Journal. 2016 ; Vol. 26, No. 1. pp. 34-37.
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