Low-temperature synthesis of nanoparticle-assembled, transparent, and low-crystallized hydroxyapatite blocks

Masahiro Okada, Tsutomu Furuzono

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

The conditions for preparing transparent blocks assembled with low-crystallized hydroxyapatite (HAp) nanoparticles were examined. An aqueous dispersion of 32-nm-sized HAp nanoparticles was prepared by a wet chemical process at room temperature (18-22°C), and then the nanoparticle-assembled block was prepared by casting the dispersion at 60°C. We also proposed a novel casting method on flowable substrates to fabricate crack-free nanoparticle-assembled blocks, because large and thick blocks were not obtained by a conventional casting method on solid substrates due to crack formation. The nanoparticle-assembled transparent HAp had nanosized pores among the particles. Cell adhesion and proliferation on the block could be directly observed with an optical microscope.

Original languageEnglish
Pages (from-to)457-462
Number of pages6
JournalJournal of Colloid and Interface Science
Volume360
Issue number2
DOIs
Publication statusPublished - Aug 15 2011
Externally publishedYes

Fingerprint

Durapatite
Hydroxyapatite
Nanoparticles
Casting
Temperature
Cell adhesion
Cell proliferation
Substrates
Crack initiation
Microscopes
Cracks

Keywords

  • Assembly
  • Cell adhesion
  • Hydroxyapatite
  • Nanoparticle
  • Nanopore
  • Transparent

ASJC Scopus subject areas

  • Surfaces, Coatings and Films
  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Colloid and Surface Chemistry

Cite this

Low-temperature synthesis of nanoparticle-assembled, transparent, and low-crystallized hydroxyapatite blocks. / Okada, Masahiro; Furuzono, Tsutomu.

In: Journal of Colloid and Interface Science, Vol. 360, No. 2, 15.08.2011, p. 457-462.

Research output: Contribution to journalArticle

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