Low dose X-ray irradiation induces stress proteins but does not prevent gastric mucosal lesion

Eisuke F. Sato, Kiyonori Yamaoka, Hidenori Yu, Seiji Morishita, Masayasu Inoue

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

We studied the effect of low dose X-ray irradiation on the expression of stress proteins and gastric mucosal lesion. Low X-ray irradiation induced the expression of mRNA for heme oxygenase in adrenal and stomach. The expression hsp70 mRNA was also induced by low dose X-ray irradiation in the adrenal gland but not in the stomach. However, the expression of Mn-SOD mRNA was not changed in either tissue by low dose X-ray irradiation. Nor was WIR stress-induced gastric mucosal lesion prevented by pre-irradiation. These data suggest that low dose X-ray irradiation induced stress proteins in some specific tissues only. It did not prevent the gastric mucosal lesion.

Original languageEnglish
Pages (from-to)103-109
Number of pages7
JournalPhysiological Chemistry and Physics and Medical NMR
Volume28
Issue number2
Publication statusPublished - 1996
Externally publishedYes

Fingerprint

Heat-Shock Proteins
Dosimetry
Stomach
X-Rays
Irradiation
X rays
Messenger RNA
Heme Oxygenase (Decyclizing)
Tissue
Adrenal Glands
Superoxide Dismutase

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Biochemistry
  • Biophysics
  • Physiology
  • Physiology (medical)
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Low dose X-ray irradiation induces stress proteins but does not prevent gastric mucosal lesion. / Sato, Eisuke F.; Yamaoka, Kiyonori; Yu, Hidenori; Morishita, Seiji; Inoue, Masayasu.

In: Physiological Chemistry and Physics and Medical NMR, Vol. 28, No. 2, 1996, p. 103-109.

Research output: Contribution to journalArticle

Sato, Eisuke F. ; Yamaoka, Kiyonori ; Yu, Hidenori ; Morishita, Seiji ; Inoue, Masayasu. / Low dose X-ray irradiation induces stress proteins but does not prevent gastric mucosal lesion. In: Physiological Chemistry and Physics and Medical NMR. 1996 ; Vol. 28, No. 2. pp. 103-109.
@article{665eef1d6a5143e2a2183d451fe3d99c,
title = "Low dose X-ray irradiation induces stress proteins but does not prevent gastric mucosal lesion",
abstract = "We studied the effect of low dose X-ray irradiation on the expression of stress proteins and gastric mucosal lesion. Low X-ray irradiation induced the expression of mRNA for heme oxygenase in adrenal and stomach. The expression hsp70 mRNA was also induced by low dose X-ray irradiation in the adrenal gland but not in the stomach. However, the expression of Mn-SOD mRNA was not changed in either tissue by low dose X-ray irradiation. Nor was WIR stress-induced gastric mucosal lesion prevented by pre-irradiation. These data suggest that low dose X-ray irradiation induced stress proteins in some specific tissues only. It did not prevent the gastric mucosal lesion.",
author = "Sato, {Eisuke F.} and Kiyonori Yamaoka and Hidenori Yu and Seiji Morishita and Masayasu Inoue",
year = "1996",
language = "English",
volume = "28",
pages = "103--109",
journal = "Physiological chemistry and physics",
issn = "0748-6642",
publisher = "Pacific Press Inc.",
number = "2",

}

TY - JOUR

T1 - Low dose X-ray irradiation induces stress proteins but does not prevent gastric mucosal lesion

AU - Sato, Eisuke F.

AU - Yamaoka, Kiyonori

AU - Yu, Hidenori

AU - Morishita, Seiji

AU - Inoue, Masayasu

PY - 1996

Y1 - 1996

N2 - We studied the effect of low dose X-ray irradiation on the expression of stress proteins and gastric mucosal lesion. Low X-ray irradiation induced the expression of mRNA for heme oxygenase in adrenal and stomach. The expression hsp70 mRNA was also induced by low dose X-ray irradiation in the adrenal gland but not in the stomach. However, the expression of Mn-SOD mRNA was not changed in either tissue by low dose X-ray irradiation. Nor was WIR stress-induced gastric mucosal lesion prevented by pre-irradiation. These data suggest that low dose X-ray irradiation induced stress proteins in some specific tissues only. It did not prevent the gastric mucosal lesion.

AB - We studied the effect of low dose X-ray irradiation on the expression of stress proteins and gastric mucosal lesion. Low X-ray irradiation induced the expression of mRNA for heme oxygenase in adrenal and stomach. The expression hsp70 mRNA was also induced by low dose X-ray irradiation in the adrenal gland but not in the stomach. However, the expression of Mn-SOD mRNA was not changed in either tissue by low dose X-ray irradiation. Nor was WIR stress-induced gastric mucosal lesion prevented by pre-irradiation. These data suggest that low dose X-ray irradiation induced stress proteins in some specific tissues only. It did not prevent the gastric mucosal lesion.

UR - http://www.scopus.com/inward/record.url?scp=0030340471&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0030340471&partnerID=8YFLogxK

M3 - Article

C2 - 8946769

AN - SCOPUS:0030340471

VL - 28

SP - 103

EP - 109

JO - Physiological chemistry and physics

JF - Physiological chemistry and physics

SN - 0748-6642

IS - 2

ER -