Low dose X-ray irradiation induces stress proteins but does not prevent gastric mucosal lesion

Eisuke F. Sato, Kiyonori Yamaoka, Hidenori Yu, Seiji Morishita, Masayasu Inoue

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

We studied the effect of low dose X-ray irradiation on the expression of stress proteins and gastric mucosal lesion. Low X-ray irradiation induced the expression of mRNA for heme oxygenase in adrenal and stomach. The expression hsp70 mRNA was also induced by low dose X-ray irradiation in the adrenal gland but not in the stomach. However, the expression of Mn-SOD mRNA was not changed in either tissue by low dose X-ray irradiation. Nor was WIR stress-induced gastric mucosal lesion prevented by pre-irradiation. These data suggest that low dose X-ray irradiation induced stress proteins in some specific tissues only. It did not prevent the gastric mucosal lesion.

Original languageEnglish
Pages (from-to)103-109
Number of pages7
JournalPhysiological chemistry and physics and medical NMR
Volume28
Issue number2
Publication statusPublished - 1996
Externally publishedYes

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Physiology
  • Spectroscopy

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