Abstract
We previously demonstrated that a swept-source optical coherence tomography system (SS-OCT) without polarization-sensing could quantitatively estimate the progress of cavitated dentin lesions in vitro. The purpose of the current study was to investigate the ability to estimate the lesion development in non-cavitated dentin lesions with a surface layer. Bovine root dentin specimens were subjected to different periods of demineralization (1 to 14 days). Cross-sectional images of the specimens before and after the demineralization were captured by SS-OCT at 1310 nm center wavelength. Following each period, the specimens were cut into sections for transverse microradiography (TMR) and correlations between SS-OCT data and TMR parameters were examined. TMR images of the specimens showed subsurface lesions ranging 100 to 400 μm in lesion depth (LD) and 1,000-5,000 volume in mineral loss (ΔZ). SS-OCT images showed a boundary suggesting the lesion front. Reflectivity increased with demineralization progress. A strong correlation was found between the boundary depth from the lesion surface and LD. Integrated dB values from the lesion surface to the boundary depth before and after the demineralization (R S and R D, respectively) were calculated. There was a significant positive relationship between ΔZ and R D; but not between ΔZ and ΔR, where ΔR=R D-R S. A clear indication of surface layer thickness was not found on OCT images. In conclusion, SS-OCT system could provide quantitative estimation of caries progress in artificial subsurface dentin lesion in terms of lesion depth. Further studies are needed to investigate whether other parameters of the dentin lesion with surface layer could be determined by this technique. Study supported by Global Center of Excellence at TMDU and NCGG.
| Original language | English |
|---|---|
| Title of host publication | Lasers in Dentistry XVIII |
| Volume | 8208 |
| DOIs | |
| Publication status | Published - 2012 |
| Externally published | Yes |
| Event | Lasers in Dentistry XVIII - San Francisco, CA, United States Duration: Jan 22 2012 → Jan 22 2012 |
Other
| Other | Lasers in Dentistry XVIII |
|---|---|
| Country | United States |
| City | San Francisco, CA |
| Period | 1/22/12 → 1/22/12 |
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Keywords
- Dentin
- Diagnosis
- SS-OCT
- Subsurface lesion
- TMR
ASJC Scopus subject areas
- Atomic and Molecular Physics, and Optics
- Electronic, Optical and Magnetic Materials
- Biomaterials
- Radiology Nuclear Medicine and imaging
Cite this
Longitudinal assessment of subsurface artificial root caries lesions by optical coherence tomography in comparison with transverse microradiography. / Sadr, Alireza; Nakashima, Syozi; Shimada, Yasushi; Tagami, Junji; Sumi, Yasunori.
Lasers in Dentistry XVIII. Vol. 8208 2012. 82080H.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Longitudinal assessment of subsurface artificial root caries lesions by optical coherence tomography in comparison with transverse microradiography
AU - Sadr, Alireza
AU - Nakashima, Syozi
AU - Shimada, Yasushi
AU - Tagami, Junji
AU - Sumi, Yasunori
PY - 2012
Y1 - 2012
N2 - We previously demonstrated that a swept-source optical coherence tomography system (SS-OCT) without polarization-sensing could quantitatively estimate the progress of cavitated dentin lesions in vitro. The purpose of the current study was to investigate the ability to estimate the lesion development in non-cavitated dentin lesions with a surface layer. Bovine root dentin specimens were subjected to different periods of demineralization (1 to 14 days). Cross-sectional images of the specimens before and after the demineralization were captured by SS-OCT at 1310 nm center wavelength. Following each period, the specimens were cut into sections for transverse microradiography (TMR) and correlations between SS-OCT data and TMR parameters were examined. TMR images of the specimens showed subsurface lesions ranging 100 to 400 μm in lesion depth (LD) and 1,000-5,000 volume in mineral loss (ΔZ). SS-OCT images showed a boundary suggesting the lesion front. Reflectivity increased with demineralization progress. A strong correlation was found between the boundary depth from the lesion surface and LD. Integrated dB values from the lesion surface to the boundary depth before and after the demineralization (R S and R D, respectively) were calculated. There was a significant positive relationship between ΔZ and R D; but not between ΔZ and ΔR, where ΔR=R D-R S. A clear indication of surface layer thickness was not found on OCT images. In conclusion, SS-OCT system could provide quantitative estimation of caries progress in artificial subsurface dentin lesion in terms of lesion depth. Further studies are needed to investigate whether other parameters of the dentin lesion with surface layer could be determined by this technique. Study supported by Global Center of Excellence at TMDU and NCGG.
AB - We previously demonstrated that a swept-source optical coherence tomography system (SS-OCT) without polarization-sensing could quantitatively estimate the progress of cavitated dentin lesions in vitro. The purpose of the current study was to investigate the ability to estimate the lesion development in non-cavitated dentin lesions with a surface layer. Bovine root dentin specimens were subjected to different periods of demineralization (1 to 14 days). Cross-sectional images of the specimens before and after the demineralization were captured by SS-OCT at 1310 nm center wavelength. Following each period, the specimens were cut into sections for transverse microradiography (TMR) and correlations between SS-OCT data and TMR parameters were examined. TMR images of the specimens showed subsurface lesions ranging 100 to 400 μm in lesion depth (LD) and 1,000-5,000 volume in mineral loss (ΔZ). SS-OCT images showed a boundary suggesting the lesion front. Reflectivity increased with demineralization progress. A strong correlation was found between the boundary depth from the lesion surface and LD. Integrated dB values from the lesion surface to the boundary depth before and after the demineralization (R S and R D, respectively) were calculated. There was a significant positive relationship between ΔZ and R D; but not between ΔZ and ΔR, where ΔR=R D-R S. A clear indication of surface layer thickness was not found on OCT images. In conclusion, SS-OCT system could provide quantitative estimation of caries progress in artificial subsurface dentin lesion in terms of lesion depth. Further studies are needed to investigate whether other parameters of the dentin lesion with surface layer could be determined by this technique. Study supported by Global Center of Excellence at TMDU and NCGG.
KW - Dentin
KW - Diagnosis
KW - SS-OCT
KW - Subsurface lesion
KW - TMR
UR - http://www.scopus.com/inward/record.url?scp=84861956224&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84861956224&partnerID=8YFLogxK
U2 - 10.1117/12.910707
DO - 10.1117/12.910707
M3 - Conference contribution
SN - 9780819488510
VL - 8208
BT - Lasers in Dentistry XVIII
ER -