Long-Lasting Immune Response Induced by Recombinant Bacillus Calmette-Guérin (BCG) Secretion System

N. Wada; N. Ohara; M. Kameoka; Y. Nishino; S. Matsumoto; T. Nishiyama; M. Naito; H. Yukitake; Y. Okada; K. Ikuta; T. Yamada

doi:10.1046/j.1365-3083.1996.d01-28.x

Long-Lasting Immune Response Induced by Recombinant Bacillus Calmette-Guérin (BCG) Secretion System

N. Wada, N. Ohara, M. Kameoka, Y. Nishino, S. Matsumoto, T. Nishiyama, M. Naito, H. Yukitake, Y. Okada, K. Ikuta, T. Yamada

Research output: Contribution to journal › Article › peer-review

16 Citations (Scopus)

Abstract

The recombinant bacillus Calmette-Guérin (rBCG) secretion system utilizing an extracellular α antigen of Mycobacterium kansasii (α-K) was characterized biochemically and immunologically. The human immunodeficiency virus type1 (HIV-1) p17^gag B cell epitope fused to α-K was secreted in extremely large amounts. At least three mice out of seven inoculated with rBCG generated high titres of antibody to the epitope. The long-lasting antibody production persisted more than 14 months.

Original language	English
Pages (from-to)	202-209
Number of pages	8
Journal	Scandinavian Journal of Immunology
Volume	43
Issue number	2
DOIs	https://doi.org/10.1046/j.1365-3083.1996.d01-28.x
Publication status	Published - Jan 1 1996
Externally published	Yes

ASJC Scopus subject areas

Immunology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1046/j.1365-3083.1996.d01-28.x

Cite this

@article{5da4108d12c34b8d8eba9661e98b2233,

title = "Long-Lasting Immune Response Induced by Recombinant Bacillus Calmette-Gu{\'e}rin (BCG) Secretion System",

abstract = "The recombinant bacillus Calmette-Gu{\'e}rin (rBCG) secretion system utilizing an extracellular α antigen of Mycobacterium kansasii (α-K) was characterized biochemically and immunologically. The human immunodeficiency virus type1 (HIV-1) p17gag B cell epitope fused to α-K was secreted in extremely large amounts. At least three mice out of seven inoculated with rBCG generated high titres of antibody to the epitope. The long-lasting antibody production persisted more than 14 months.",

author = "N. Wada and N. Ohara and M. Kameoka and Y. Nishino and S. Matsumoto and T. Nishiyama and M. Naito and H. Yukitake and Y. Okada and K. Ikuta and T. Yamada",

year = "1996",

month = jan,

day = "1",

doi = "10.1046/j.1365-3083.1996.d01-28.x",

language = "English",

volume = "43",

pages = "202--209",

journal = "Scandinavian Journal of Immunology",

issn = "0300-9475",

publisher = "Wiley-Blackwell",

number = "2",

}

TY - JOUR

T1 - Long-Lasting Immune Response Induced by Recombinant Bacillus Calmette-Guérin (BCG) Secretion System

AU - Wada, N.

AU - Ohara, N.

AU - Kameoka, M.

AU - Nishino, Y.

AU - Matsumoto, S.

AU - Nishiyama, T.

AU - Naito, M.

AU - Yukitake, H.

AU - Okada, Y.

AU - Ikuta, K.

AU - Yamada, T.

PY - 1996/1/1

Y1 - 1996/1/1

N2 - The recombinant bacillus Calmette-Guérin (rBCG) secretion system utilizing an extracellular α antigen of Mycobacterium kansasii (α-K) was characterized biochemically and immunologically. The human immunodeficiency virus type1 (HIV-1) p17gag B cell epitope fused to α-K was secreted in extremely large amounts. At least three mice out of seven inoculated with rBCG generated high titres of antibody to the epitope. The long-lasting antibody production persisted more than 14 months.

AB - The recombinant bacillus Calmette-Guérin (rBCG) secretion system utilizing an extracellular α antigen of Mycobacterium kansasii (α-K) was characterized biochemically and immunologically. The human immunodeficiency virus type1 (HIV-1) p17gag B cell epitope fused to α-K was secreted in extremely large amounts. At least three mice out of seven inoculated with rBCG generated high titres of antibody to the epitope. The long-lasting antibody production persisted more than 14 months.

UR - http://www.scopus.com/inward/record.url?scp=0029671342&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0029671342&partnerID=8YFLogxK

U2 - 10.1046/j.1365-3083.1996.d01-28.x

DO - 10.1046/j.1365-3083.1996.d01-28.x

M3 - Article

C2 - 8633200

AN - SCOPUS:0029671342

VL - 43

SP - 202

EP - 209

JO - Scandinavian Journal of Immunology

JF - Scandinavian Journal of Immunology

SN - 0300-9475

IS - 2

ER -

Long-Lasting Immune Response Induced by Recombinant Bacillus Calmette-Guérin (BCG) Secretion System

Abstract

ASJC Scopus subject areas

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this