Abstract
The recombinant bacillus Calmette-Guérin (rBCG) secretion system utilizing an extracellular α antigen of Mycobacterium kansasii (α-K) was characterized biochemically and immunologically. The human immunodeficiency virus type1 (HIV-1) p17gag B cell epitope fused to α-K was secreted in extremely large amounts. At least three mice out of seven inoculated with rBCG generated high titres of antibody to the epitope. The long-lasting antibody production persisted more than 14 months.
Original language | English |
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Pages (from-to) | 202-209 |
Number of pages | 8 |
Journal | Scandinavian Journal of Immunology |
Volume | 43 |
Issue number | 2 |
DOIs | |
Publication status | Published - Jan 1 1996 |
Externally published | Yes |
ASJC Scopus subject areas
- Immunology