Localized lymph node light chain amyloidosis

Akira Yamamoto; Nobuharu Fujii; Mikako Obika; Taro Yamashita; Fumio Otsuka

doi:10.2169/internalmedicine.4651-20

Localized lymph node light chain amyloidosis

Akira Yamamoto, Nobuharu Fujii, Mikako Obika, Taro Yamashita, Fumio Otsuka

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

The prognosis of systemic amyloid light chain (AL) amyloidosis is generally poor, hence requiring chemotherapy or hematopoietic stem cell transplantation, while the prognosis of localized AL amyloidosis without an abnormal monoclonal immunoglobulin light chain is good. Localized AL amyloidosis has been previously reported to be observed in pulmonary, urinary tract, gastrointestinal, oropharyngeal, and laryngeal sites. However, only a few cases of localized lymph node AL amyloidosis have so far been reported. We herein present a case of localized lymph node AL amyloidosis that could possibly be misdiagnosed as systematic AL amyloidosis.

Original language	English
Pages (from-to)	2415-2418
Number of pages	4
Journal	Internal Medicine
Volume	59
Issue number	19
DOIs	https://doi.org/10.2169/internalmedicine.4651-20
Publication status	Published - Oct 1 2020

Keywords

Localized AL amyloidosis
Lymphadenopathy
PET-CT
Systemic AL amyloidosis

ASJC Scopus subject areas

Internal Medicine

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10.2169/internalmedicine.4651-20

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title = "Localized lymph node light chain amyloidosis",

abstract = "The prognosis of systemic amyloid light chain (AL) amyloidosis is generally poor, hence requiring chemotherapy or hematopoietic stem cell transplantation, while the prognosis of localized AL amyloidosis without an abnormal monoclonal immunoglobulin light chain is good. Localized AL amyloidosis has been previously reported to be observed in pulmonary, urinary tract, gastrointestinal, oropharyngeal, and laryngeal sites. However, only a few cases of localized lymph node AL amyloidosis have so far been reported. We herein present a case of localized lymph node AL amyloidosis that could possibly be misdiagnosed as systematic AL amyloidosis.",

keywords = "Localized AL amyloidosis, Lymphadenopathy, PET-CT, Systemic AL amyloidosis",

author = "Akira Yamamoto and Nobuharu Fujii and Mikako Obika and Taro Yamashita and Fumio Otsuka",

year = "2020",

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TY - JOUR

T1 - Localized lymph node light chain amyloidosis

AU - Yamamoto, Akira

AU - Fujii, Nobuharu

AU - Obika, Mikako

AU - Yamashita, Taro

AU - Otsuka, Fumio

PY - 2020/10/1

Y1 - 2020/10/1

N2 - The prognosis of systemic amyloid light chain (AL) amyloidosis is generally poor, hence requiring chemotherapy or hematopoietic stem cell transplantation, while the prognosis of localized AL amyloidosis without an abnormal monoclonal immunoglobulin light chain is good. Localized AL amyloidosis has been previously reported to be observed in pulmonary, urinary tract, gastrointestinal, oropharyngeal, and laryngeal sites. However, only a few cases of localized lymph node AL amyloidosis have so far been reported. We herein present a case of localized lymph node AL amyloidosis that could possibly be misdiagnosed as systematic AL amyloidosis.

AB - The prognosis of systemic amyloid light chain (AL) amyloidosis is generally poor, hence requiring chemotherapy or hematopoietic stem cell transplantation, while the prognosis of localized AL amyloidosis without an abnormal monoclonal immunoglobulin light chain is good. Localized AL amyloidosis has been previously reported to be observed in pulmonary, urinary tract, gastrointestinal, oropharyngeal, and laryngeal sites. However, only a few cases of localized lymph node AL amyloidosis have so far been reported. We herein present a case of localized lymph node AL amyloidosis that could possibly be misdiagnosed as systematic AL amyloidosis.

KW - Localized AL amyloidosis

KW - Lymphadenopathy

KW - PET-CT

KW - Systemic AL amyloidosis

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DO - 10.2169/internalmedicine.4651-20

M3 - Article

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SN - 0918-2918

VL - 59

SP - 2415

EP - 2418

JO - Internal Medicine

JF - Internal Medicine

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ER -

Localized lymph node light chain amyloidosis

Abstract

Keywords

ASJC Scopus subject areas

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