Localized lesions on MRI in a case of hypertensive brainstem encephalopathy

Yoichi Ono, Yasuhiro Manabe, Yoshiyuki Hamakawa, Tetsuro Murakami, Nobuhiko Omori, Yasuaki Hayashi, Koji Abe

Research output: Contribution to journalArticlepeer-review

14 Citations (Scopus)


We report a case of hypertensive brainstem encephalopathy (HBE) with unusual magnetic resonance imaging (MRI) findings. A 67-year-old woman presented with high blood pressure and stupor as the only symptoms. MRI revealed lesions localized in the area from the upper medulla oblongata to the lower pons with high fluid-attenuated inversion recovery (FLAIR) and T2-weighted signal intensity, but these were not seen in the whole brainstem and there were no accompanying occipital lobe changes. To our knowledge, no similar case has been reported. The lesions and symptoms dramatically improved after normalization of blood pressure. Severe hypertension that exceeded the range of autoregulation may have resulted in segmental vasodilatation and the increased vascular permeability may have lead to vasogenic edema in the localized areas of the brainstem.

Original languageEnglish
Pages (from-to)1002-1005
Number of pages4
JournalInternal Medicine
Issue number9
Publication statusPublished - Oct 28 2005


  • Hypertensive brainstem encephalopathy
  • Magnetic resonance imaging

ASJC Scopus subject areas

  • Internal Medicine


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