Living-related liver transplantation in a patient with hepatopulmonary syndrome

Masaki Matsumi, Ryuji Kaku, Hiromi Fujii, Hidetoshi Kajiwara, Toshihiro Sasaki, Tetsufumi Satoh, Ichiro Ohashi, Kiyoshi Morita

Research output: Contribution to journalArticle

Abstract

We experienced the perioperative management of the living related liver transplantation (LRLT) in a patient with hepatopulmonary syndrome (HPS). HPS is seen in 15% of patients of the endstage liver failure, and it accompanies the various types of hypoxia. The diagnostic standards of HPS are chronic liver disease usually complicated by portal hypertension with or without cirrhosis, arterial hypoxemia (PaO2<70 mmHg or A-aDO2 gradient> 20 mmHg), and intrapulmonary vascular dilation. The present case conformed to the diagnostic standard. But this case was of a mild type of HPS, because PaO2 was elevated after O2 inhalation and extrapulmonary uptake of 99mTcMAA after lung perfusion was lower than 40%. During perioperative period of LRLT, there were no complications such as hypoxia, acute rejection, bleeding and infection. Therefore HPS would be improved after LRLT. In the management of perioperative period it is important to be aware of hypoxia and to evaluate preoperatively the condition of the patient properly.

Original languageEnglish
Pages (from-to)668-671
Number of pages4
JournalJapanese Journal of Anesthesiology
Volume53
Issue number6
Publication statusPublished - Jun 1 2004

Keywords

  • Hepatopulmonary syndrome (HPS)
  • Hypoxemia
  • Living related liver transplantation

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

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