Abstract
Drosophila wings have been a model system to study the effect of HSP90 on quantitative trait variation. The effect of HSP90 inhibition on environmental buffering of wing morphology varies among studies while the genetic buffering effect of it was examined in only one study and was not detected. Variable results so far might show that the genetic background influences the environmental and genetic buffering effect of HSP90. In the previous studies, the number of the genetic backgrounds used is limited. To examine the effect of HSP90 inhibition with a larger number of genetic backgrounds than the previous studies, 20 wild-type strains of Drosophila melanogaster were used in this study. Here I investigated the effect of HSP90 inhibition on the environmental buffering of wing shape and size by assessing within-individual and among-individual variations, and as a result, I found little or very weak effects on environmental and genetic buffering. The current results suggest that the role of HSP90 as a global regulator of environmental and genetic buffering is limited at least in quantitative traits.
| Original language | English |
|---|---|
| Pages (from-to) | 9-18 |
| Number of pages | 10 |
| Journal | Genetica |
| Volume | 145 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - Feb 1 2017 |
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Keywords
- Among-individual variation
- Cryptic genetic variation
- Fluctuating asymmetry
- Geometric morphometrics
ASJC Scopus subject areas
- Animal Science and Zoology
- Genetics
- Plant Science
- Insect Science
Cite this
Little effect of HSP90 inhibition on the quantitative wing traits variation in Drosophila melanogaster. / Takahashi, Kazuo.
In: Genetica, Vol. 145, No. 1, 01.02.2017, p. 9-18.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Little effect of HSP90 inhibition on the quantitative wing traits variation in Drosophila melanogaster
AU - Takahashi, Kazuo
PY - 2017/2/1
Y1 - 2017/2/1
N2 - Drosophila wings have been a model system to study the effect of HSP90 on quantitative trait variation. The effect of HSP90 inhibition on environmental buffering of wing morphology varies among studies while the genetic buffering effect of it was examined in only one study and was not detected. Variable results so far might show that the genetic background influences the environmental and genetic buffering effect of HSP90. In the previous studies, the number of the genetic backgrounds used is limited. To examine the effect of HSP90 inhibition with a larger number of genetic backgrounds than the previous studies, 20 wild-type strains of Drosophila melanogaster were used in this study. Here I investigated the effect of HSP90 inhibition on the environmental buffering of wing shape and size by assessing within-individual and among-individual variations, and as a result, I found little or very weak effects on environmental and genetic buffering. The current results suggest that the role of HSP90 as a global regulator of environmental and genetic buffering is limited at least in quantitative traits.
AB - Drosophila wings have been a model system to study the effect of HSP90 on quantitative trait variation. The effect of HSP90 inhibition on environmental buffering of wing morphology varies among studies while the genetic buffering effect of it was examined in only one study and was not detected. Variable results so far might show that the genetic background influences the environmental and genetic buffering effect of HSP90. In the previous studies, the number of the genetic backgrounds used is limited. To examine the effect of HSP90 inhibition with a larger number of genetic backgrounds than the previous studies, 20 wild-type strains of Drosophila melanogaster were used in this study. Here I investigated the effect of HSP90 inhibition on the environmental buffering of wing shape and size by assessing within-individual and among-individual variations, and as a result, I found little or very weak effects on environmental and genetic buffering. The current results suggest that the role of HSP90 as a global regulator of environmental and genetic buffering is limited at least in quantitative traits.
KW - Among-individual variation
KW - Cryptic genetic variation
KW - Fluctuating asymmetry
KW - Geometric morphometrics
UR - http://www.scopus.com/inward/record.url?scp=85000936673&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85000936673&partnerID=8YFLogxK
U2 - 10.1007/s10709-016-9940-z
DO - 10.1007/s10709-016-9940-z
M3 - Article
C2 - 27909948
AN - SCOPUS:85000936673
VL - 145
SP - 9
EP - 18
JO - Genetica
JF - Genetica
SN - 0016-6707
IS - 1
ER -