Liquid phase deposited titania coating to enable in vitro apatite formation on Ti6Al4V alloy

Satoshi Hayakawa, Yoshitake Masuda, Keigo Okamoto, Yuki Shirosaki, Kazumi Kato, Akiyoshi Osaka

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

A recently developed "GRAPE® technology" provides titanium or titanium alloy implants with spontaneous apatite-forming ability in vitro, which requires properly designed gaps and optimum heat treatment in air. In this study, titanium alloy and commercially pure (cp) titanium substrates were thermally oxidized in air before aligning pairs of specimens in the GRAPE® set-up, i.e., titanium alloy and cp titanium substrates were aligned parallel to each other with optimum gap width (spatial design). A liquid phase deposition (LPD) technique was employed for titania coatings on titanium alloy substrate. Then, they were soaked in Kokubo's simulated body fluid (SBF, pH 7.4, 36.5 C) for 7 days to confirm the in vitro apatite formation on the substrates under the specific spatial design. Anatase-type titania coatings fabricated by using LPD technique led to the deposition of apatite particles within 7 days and showed apatite X-ray diffraction. On the other hand, thermally oxidized titanium alloy substrate in air and non-treated specimens did not show any apatite X-ray diffraction. These results indicated that the heterogeneous nucleation of apatite induced on anatase-type titania coating prepared by LPD technique when it was aligned parallel to thermally oxidized cp titanium substrate with optimum gap width.

Original languageEnglish
Pages (from-to)375-381
Number of pages7
JournalJournal of Materials Science: Materials in Medicine
Volume25
Issue number2
DOIs
Publication statusPublished - Feb 2014

Fingerprint

Apatites
Apatite
Titanium
Titanium alloys
Coatings
Liquids
Substrates
Titanium dioxide
Air
X-Ray Diffraction
X ray diffraction
Body fluids
titanium dioxide
titanium alloy (TiAl6V4)
In Vitro Techniques
Nucleation
Heat treatment
Body Fluids
Hot Temperature
Technology

ASJC Scopus subject areas

  • Biophysics
  • Biomaterials
  • Bioengineering
  • Biomedical Engineering

Cite this

Liquid phase deposited titania coating to enable in vitro apatite formation on Ti6Al4V alloy. / Hayakawa, Satoshi; Masuda, Yoshitake; Okamoto, Keigo; Shirosaki, Yuki; Kato, Kazumi; Osaka, Akiyoshi.

In: Journal of Materials Science: Materials in Medicine, Vol. 25, No. 2, 02.2014, p. 375-381.

Research output: Contribution to journalArticle

Hayakawa, Satoshi ; Masuda, Yoshitake ; Okamoto, Keigo ; Shirosaki, Yuki ; Kato, Kazumi ; Osaka, Akiyoshi. / Liquid phase deposited titania coating to enable in vitro apatite formation on Ti6Al4V alloy. In: Journal of Materials Science: Materials in Medicine. 2014 ; Vol. 25, No. 2. pp. 375-381.
@article{6c875ec9f0f441d8b5232d2a98d5ce6c,
title = "Liquid phase deposited titania coating to enable in vitro apatite formation on Ti6Al4V alloy",
abstract = "A recently developed {"}GRAPE{\circledR} technology{"} provides titanium or titanium alloy implants with spontaneous apatite-forming ability in vitro, which requires properly designed gaps and optimum heat treatment in air. In this study, titanium alloy and commercially pure (cp) titanium substrates were thermally oxidized in air before aligning pairs of specimens in the GRAPE{\circledR} set-up, i.e., titanium alloy and cp titanium substrates were aligned parallel to each other with optimum gap width (spatial design). A liquid phase deposition (LPD) technique was employed for titania coatings on titanium alloy substrate. Then, they were soaked in Kokubo's simulated body fluid (SBF, pH 7.4, 36.5 C) for 7 days to confirm the in vitro apatite formation on the substrates under the specific spatial design. Anatase-type titania coatings fabricated by using LPD technique led to the deposition of apatite particles within 7 days and showed apatite X-ray diffraction. On the other hand, thermally oxidized titanium alloy substrate in air and non-treated specimens did not show any apatite X-ray diffraction. These results indicated that the heterogeneous nucleation of apatite induced on anatase-type titania coating prepared by LPD technique when it was aligned parallel to thermally oxidized cp titanium substrate with optimum gap width.",
author = "Satoshi Hayakawa and Yoshitake Masuda and Keigo Okamoto and Yuki Shirosaki and Kazumi Kato and Akiyoshi Osaka",
year = "2014",
month = "2",
doi = "10.1007/s10856-013-5078-z",
language = "English",
volume = "25",
pages = "375--381",
journal = "Journal of Materials Science: Materials in Medicine",
issn = "0957-4530",
publisher = "Springer Netherlands",
number = "2",

}

TY - JOUR

T1 - Liquid phase deposited titania coating to enable in vitro apatite formation on Ti6Al4V alloy

AU - Hayakawa, Satoshi

AU - Masuda, Yoshitake

AU - Okamoto, Keigo

AU - Shirosaki, Yuki

AU - Kato, Kazumi

AU - Osaka, Akiyoshi

PY - 2014/2

Y1 - 2014/2

N2 - A recently developed "GRAPE® technology" provides titanium or titanium alloy implants with spontaneous apatite-forming ability in vitro, which requires properly designed gaps and optimum heat treatment in air. In this study, titanium alloy and commercially pure (cp) titanium substrates were thermally oxidized in air before aligning pairs of specimens in the GRAPE® set-up, i.e., titanium alloy and cp titanium substrates were aligned parallel to each other with optimum gap width (spatial design). A liquid phase deposition (LPD) technique was employed for titania coatings on titanium alloy substrate. Then, they were soaked in Kokubo's simulated body fluid (SBF, pH 7.4, 36.5 C) for 7 days to confirm the in vitro apatite formation on the substrates under the specific spatial design. Anatase-type titania coatings fabricated by using LPD technique led to the deposition of apatite particles within 7 days and showed apatite X-ray diffraction. On the other hand, thermally oxidized titanium alloy substrate in air and non-treated specimens did not show any apatite X-ray diffraction. These results indicated that the heterogeneous nucleation of apatite induced on anatase-type titania coating prepared by LPD technique when it was aligned parallel to thermally oxidized cp titanium substrate with optimum gap width.

AB - A recently developed "GRAPE® technology" provides titanium or titanium alloy implants with spontaneous apatite-forming ability in vitro, which requires properly designed gaps and optimum heat treatment in air. In this study, titanium alloy and commercially pure (cp) titanium substrates were thermally oxidized in air before aligning pairs of specimens in the GRAPE® set-up, i.e., titanium alloy and cp titanium substrates were aligned parallel to each other with optimum gap width (spatial design). A liquid phase deposition (LPD) technique was employed for titania coatings on titanium alloy substrate. Then, they were soaked in Kokubo's simulated body fluid (SBF, pH 7.4, 36.5 C) for 7 days to confirm the in vitro apatite formation on the substrates under the specific spatial design. Anatase-type titania coatings fabricated by using LPD technique led to the deposition of apatite particles within 7 days and showed apatite X-ray diffraction. On the other hand, thermally oxidized titanium alloy substrate in air and non-treated specimens did not show any apatite X-ray diffraction. These results indicated that the heterogeneous nucleation of apatite induced on anatase-type titania coating prepared by LPD technique when it was aligned parallel to thermally oxidized cp titanium substrate with optimum gap width.

UR - http://www.scopus.com/inward/record.url?scp=84894417086&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84894417086&partnerID=8YFLogxK

U2 - 10.1007/s10856-013-5078-z

DO - 10.1007/s10856-013-5078-z

M3 - Article

C2 - 24165799

AN - SCOPUS:84894417086

VL - 25

SP - 375

EP - 381

JO - Journal of Materials Science: Materials in Medicine

JF - Journal of Materials Science: Materials in Medicine

SN - 0957-4530

IS - 2

ER -