Liquid-Liquid Phase Transition Drives Intra-chloroplast Cargo Sorting

Min Ouyang, Xiaoyi Li, Jing Zhang, Peiqiang Feng, Hua Pu, Lingxi Kong, Zechen Bai, Liwei Rong, Xiumei Xu, Wei Chi, Qiang Wang, Fan Chen, Congming Lu, Jianren Shen, Lixin Zhang

    Research output: Contribution to journalArticlepeer-review

    22 Citations (Scopus)

    Abstract

    A pair of ankyrin repeat proteins in chloroplasts recognizes signal peptides on thylakoid-bound cargo proteins and undergoes liquid-liquid phase separation to facilitate their sorting and transport.

    Original languageEnglish
    Pages (from-to)1144-1159.e20
    JournalCell
    Volume180
    Issue number6
    DOIs
    Publication statusPublished - Mar 19 2020

    Keywords

    • ankyrin-repeat proteins
    • cargo sorting
    • chloroplast
    • intrinsically disordered regions
    • liquid-liquid phase separation
    • nuclear-encoded chloroplast proteins
    • thylakoid membranes
    • twin arginine translocation pathway

    ASJC Scopus subject areas

    • Biochemistry, Genetics and Molecular Biology(all)

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