Abstract
Background. Liposarcoma of the chest wall is extremely rare. To the best of our knowledge, only 23 cases have been reported, including the present case. Case. A 39-year-old woman complaining of lumbago and right leg pain visited a local clinic. Radiological studies demonstrated abnormal shadows in the left pleural cavity, right lumbar area, and left kidney and she was referred to our hospital. A CT-guided needle biopsy of the chest tumor revealed a liposarcoma. Thereafter, since the patient experienced dyspnea caused by a rapid growth of the chest tumor, it was resected. The pathological diagnosis of the tumor was a myxoid liposarcoma that included round cell neoplasm components. The patient was given an ambulatory discharge following concurrent chemoradiation therapy (CRT) including cisplatin to the chest wall and lumbar area. However, she was readmitted 4 months later, because of multiple metastases in the lung, liver, thigh, and pelvis. Radiation therapy and chemotherapy were effective to suppress the rapid growth of the metastatic lesions, and the metastatic lesion in the thigh was particularly well controlled. Although the patient died 1 year and 2 months after surgery, autopsy revealed no recurrence in the chest wall. Conclusion. Surgical resection and postoperative CRT were considered to be effective for local control of a liposarcoma of the chest wall. Furthermore, the CRT seemed to be also effective for control of the metastatic lesions.
| Original language | English |
|---|---|
| Pages (from-to) | 753-758 |
| Number of pages | 6 |
| Journal | Japanese Journal of Lung Cancer |
| Volume | 46 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - Oct 2006 |
| Externally published | Yes |
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Keywords
- Concurrent chemoradiation therapy
- Intrathoracic liposarcoma
- Liposarcoma of the chest wall
- Pleural cavity
- Surgical resection
ASJC Scopus subject areas
- Oncology
- Pulmonary and Respiratory Medicine
Cite this
Liposarcoma of the chest wall - Case report and review of literature. / Kobayashi, Satoru; Sawabata, Noriyoshi; Karube, Yoko; Yoshii, Naoko; Honma, Koichi; Miyoshi, Shinichiro.
In: Japanese Journal of Lung Cancer, Vol. 46, No. 6, 10.2006, p. 753-758.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Liposarcoma of the chest wall - Case report and review of literature
AU - Kobayashi, Satoru
AU - Sawabata, Noriyoshi
AU - Karube, Yoko
AU - Yoshii, Naoko
AU - Honma, Koichi
AU - Miyoshi, Shinichiro
PY - 2006/10
Y1 - 2006/10
N2 - Background. Liposarcoma of the chest wall is extremely rare. To the best of our knowledge, only 23 cases have been reported, including the present case. Case. A 39-year-old woman complaining of lumbago and right leg pain visited a local clinic. Radiological studies demonstrated abnormal shadows in the left pleural cavity, right lumbar area, and left kidney and she was referred to our hospital. A CT-guided needle biopsy of the chest tumor revealed a liposarcoma. Thereafter, since the patient experienced dyspnea caused by a rapid growth of the chest tumor, it was resected. The pathological diagnosis of the tumor was a myxoid liposarcoma that included round cell neoplasm components. The patient was given an ambulatory discharge following concurrent chemoradiation therapy (CRT) including cisplatin to the chest wall and lumbar area. However, she was readmitted 4 months later, because of multiple metastases in the lung, liver, thigh, and pelvis. Radiation therapy and chemotherapy were effective to suppress the rapid growth of the metastatic lesions, and the metastatic lesion in the thigh was particularly well controlled. Although the patient died 1 year and 2 months after surgery, autopsy revealed no recurrence in the chest wall. Conclusion. Surgical resection and postoperative CRT were considered to be effective for local control of a liposarcoma of the chest wall. Furthermore, the CRT seemed to be also effective for control of the metastatic lesions.
AB - Background. Liposarcoma of the chest wall is extremely rare. To the best of our knowledge, only 23 cases have been reported, including the present case. Case. A 39-year-old woman complaining of lumbago and right leg pain visited a local clinic. Radiological studies demonstrated abnormal shadows in the left pleural cavity, right lumbar area, and left kidney and she was referred to our hospital. A CT-guided needle biopsy of the chest tumor revealed a liposarcoma. Thereafter, since the patient experienced dyspnea caused by a rapid growth of the chest tumor, it was resected. The pathological diagnosis of the tumor was a myxoid liposarcoma that included round cell neoplasm components. The patient was given an ambulatory discharge following concurrent chemoradiation therapy (CRT) including cisplatin to the chest wall and lumbar area. However, she was readmitted 4 months later, because of multiple metastases in the lung, liver, thigh, and pelvis. Radiation therapy and chemotherapy were effective to suppress the rapid growth of the metastatic lesions, and the metastatic lesion in the thigh was particularly well controlled. Although the patient died 1 year and 2 months after surgery, autopsy revealed no recurrence in the chest wall. Conclusion. Surgical resection and postoperative CRT were considered to be effective for local control of a liposarcoma of the chest wall. Furthermore, the CRT seemed to be also effective for control of the metastatic lesions.
KW - Concurrent chemoradiation therapy
KW - Intrathoracic liposarcoma
KW - Liposarcoma of the chest wall
KW - Pleural cavity
KW - Surgical resection
UR - http://www.scopus.com/inward/record.url?scp=33845340780&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33845340780&partnerID=8YFLogxK
U2 - 10.2482/haigan.46.753
DO - 10.2482/haigan.46.753
M3 - Article
AN - SCOPUS:33845340780
VL - 46
SP - 753
EP - 758
JO - Japanese Journal of Lung Cancer
JF - Japanese Journal of Lung Cancer
SN - 0386-9628
IS - 6
ER -