Limited mediastinal lymph node dissection for non-small cell lung cancer according to intraoperative histologic examinations

Tatsuya Yoshimasu, Shinichiro Miyoshi, Shoji Oura, Issei Hirai, Yozo Kokawa, Yoshitaka Okamura

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

Background: Although radioisotopic procedures are commonly used to detect sentinel lymph nodes in breast cancer surgery, these procedures are often problematic and not necessarily suitable for lung cancer surgery. Methods: Our previous study revealed that the mediastinal sentinel lymph node, defined as the regional mediastinal lymph node, consisted of nodes 2, 3, or 4 in right upper lobe cancers; 3, 7, or 8 in right lower lobe cancers; 4, 5, or 7 in left upper lobe cancers; and 4, 7, or 8 in left lower lobe cancers. On the basis of these findings, we pathologically investigated one representative lymph node at each of the 3 levels dissected during surgical intervention in 69 patients with non-small cell lung cancer from September 1993 through December 2002. Fifty-eight patients with lung cancer underwent lobectomies with limited mediastinal lymph node dissection according to this strategy. Results: Mediastinal lymph node recurrence was observed in only one patient during 41 ± 25 months (maximum, 98 months) of follow-up. The cancer-specific 5-year survivals were 96.6% in patients with pathologic stage IA disease (n = 31) and 67.4% in patients with stage IB disease (n = 16). Conclusion: These results suggested that limited mediastinal lymph node dissection is applicable to patients with non-small cell lung cancer whose regional mediastinal lymph nodes are not metastatic.

Original languageEnglish
Pages (from-to)433-437
Number of pages5
JournalJournal of Thoracic and Cardiovascular Surgery
Volume130
Issue number2
DOIs
Publication statusPublished - Aug 2005
Externally publishedYes

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Lymph Node Excision
Non-Small Cell Lung Carcinoma
Lymph Nodes
Neoplasms
Lung Neoplasms
Breast Neoplasms
Recurrence
Survival

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery

Cite this

Limited mediastinal lymph node dissection for non-small cell lung cancer according to intraoperative histologic examinations. / Yoshimasu, Tatsuya; Miyoshi, Shinichiro; Oura, Shoji; Hirai, Issei; Kokawa, Yozo; Okamura, Yoshitaka.

In: Journal of Thoracic and Cardiovascular Surgery, Vol. 130, No. 2, 08.2005, p. 433-437.

Research output: Contribution to journalArticle

Yoshimasu, Tatsuya ; Miyoshi, Shinichiro ; Oura, Shoji ; Hirai, Issei ; Kokawa, Yozo ; Okamura, Yoshitaka. / Limited mediastinal lymph node dissection for non-small cell lung cancer according to intraoperative histologic examinations. In: Journal of Thoracic and Cardiovascular Surgery. 2005 ; Vol. 130, No. 2. pp. 433-437.
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