Limb regeneration in Xenopus laevis froglet

Makoto Suzuki, Nayuta Yakushiji, Yasuaki Nakada, Akira Satoh, Hiroyuki Ide, Koji Tamura

Research output: Contribution to journalReview article

53 Citations (Scopus)

Abstract

Limb regeneration in amphibians is a representative process of epimorphosis. This type of organ regeneration, in which a mass of undifferentiated cells referred to as the "blastema" proliferate to restore the lost part of the amputated organ, is distinct from morphallaxis as observed, for instance, in Hydra, in which rearrangement of pre-existing cells and tissues mainly contribute to regeneration. In contrast to complete limb regeneration in urodele amphibians, limb regeneration in Xenopus, an anuran amphibian, is restricted. In this review of some aspects regarding adult limb regeneration in Xenopus laevis, we suggest that limb regeneration in adult Xenopus, which is pattern/tissue deficient, also represents epimorphosis.

Original languageEnglish
Pages (from-to)26-37
Number of pages12
JournalTheScientificWorldJournal
Volume6
Issue numberSUPPL.1
DOIs
Publication statusPublished - May 12 2006
Externally publishedYes

Keywords

  • Blastema
  • Dedifferentiation
  • Epimorphosis
  • Limb regeneration
  • Muscle regeneration
  • Nerve dependence
  • Spike
  • Wound healing
  • Xenopus

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Environmental Science(all)

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  • Cite this

    Suzuki, M., Yakushiji, N., Nakada, Y., Satoh, A., Ide, H., & Tamura, K. (2006). Limb regeneration in Xenopus laevis froglet. TheScientificWorldJournal, 6(SUPPL.1), 26-37. https://doi.org/10.1100/tsw.2006.325