Leukocytes in the glomerular capillary lumen in Masugi nephritis. A scanning electron microscopic study of freeze-cracked specimens

H. Makino; M. Takaoka; K. Komoda; K. Tokuyama; Z. Ota; T. Ofuji; T. Kaneshige

Leukocytes in the glomerular capillary lumen in Masugi nephritis. A scanning electron microscopic study of freeze-cracked specimens

H. Makino, M. Takaoka, K. Komoda, K. Tokuyama, Z. Ota, T. Ofuji, T. Kaneshige

Research output: Contribution to journal › Article › peer-review

Abstract

Masugi nephritis was induced in rats by a single intravenous injection of rabbit anti-rat kidney serum, and studied with a scanning electron microscope. A characteristic finding was the presence of white cells, probably polymorphonuclear leukocytes, with many microspikes which penetrated through degenerated glomerular endothelial cells to be in direct contact with the glomerular basement membrane. This finding confirms the pathogenic role of leukocytes in glomerulonephritis induced by anti-glomerular basement membrane antibody.

Original language	English
Pages (from-to)	373-376
Number of pages	4
Journal	Acta medica Okayama
Volume	35
Issue number	5
Publication status	Published - Dec 1 1981

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

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abstract = "Masugi nephritis was induced in rats by a single intravenous injection of rabbit anti-rat kidney serum, and studied with a scanning electron microscope. A characteristic finding was the presence of white cells, probably polymorphonuclear leukocytes, with many microspikes which penetrated through degenerated glomerular endothelial cells to be in direct contact with the glomerular basement membrane. This finding confirms the pathogenic role of leukocytes in glomerulonephritis induced by anti-glomerular basement membrane antibody.",

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AU - Makino, H.

AU - Takaoka, M.

AU - Komoda, K.

AU - Tokuyama, K.

AU - Ota, Z.

AU - Ofuji, T.

AU - Kaneshige, T.

PY - 1981/12/1

Y1 - 1981/12/1

N2 - Masugi nephritis was induced in rats by a single intravenous injection of rabbit anti-rat kidney serum, and studied with a scanning electron microscope. A characteristic finding was the presence of white cells, probably polymorphonuclear leukocytes, with many microspikes which penetrated through degenerated glomerular endothelial cells to be in direct contact with the glomerular basement membrane. This finding confirms the pathogenic role of leukocytes in glomerulonephritis induced by anti-glomerular basement membrane antibody.

AB - Masugi nephritis was induced in rats by a single intravenous injection of rabbit anti-rat kidney serum, and studied with a scanning electron microscope. A characteristic finding was the presence of white cells, probably polymorphonuclear leukocytes, with many microspikes which penetrated through degenerated glomerular endothelial cells to be in direct contact with the glomerular basement membrane. This finding confirms the pathogenic role of leukocytes in glomerulonephritis induced by anti-glomerular basement membrane antibody.

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ER -

Leukocytes in the glomerular capillary lumen in Masugi nephritis. A scanning electron microscopic study of freeze-cracked specimens

Abstract

ASJC Scopus subject areas

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