Leiomyosarcoma in the pharynx; A case report

Primary leiomyosarcoma of the pharynx is extremely rare. A review of the literature revealed only 7 cases of pharyngeal leiomyosarcoma in Japan. We describe the case of a 72-year-old man with a leiomyosarcoma of the middle pharynx in this paper. Seven years ago, the patient had a malignant melanoma of the pharynx, and total extirpation of the tumor was performed with reconstruction of the pharynx using a pectoralis major myocutaneous flap, irradiation (20 Gy), and chemotherapy. In this case, leiomyosarcoma arising from the pharynx occurred in the irradiation field. Only 12 cases of radiation-induced leiomyosarcoma have been reported in the Japanese and foreign literature.