Left ventricular ejection and filling rate measurement based on the automatic edge detection method of ECG-gated blood pool single-photon emission tomography

Takahiro Higuchi, Junichi Taki, Kenichi Nakajima, Seigo Kinuya, Masatoshi Ikeda, Masanobu Namura, Norihisa Tonami

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

The objective of the present investigation was to determine the feasibility of assessing left ventricular systolic ejection and diastolic filling via the automatic edge detection method employing ECG-gated blood pool single-photon emission tomography (SPET GBP) data. Methods: Thirty-five patients, who had undergone both SPET GBP and ECG-gated equilibrium blood pool scintigraphy by the planar method (planar GBP), were enrolled in this study. Planar GBP was performed with a single-headed gamma camera. From the left anterior oblique projection, data were acquired at 24 frames/cardiac cycle with ECG-gating during the equilibrium state. SPET GBP was conducted utilizing a triple-headed gamma camera, with 60 projection views over 360 degrees by 60 sec per view, in 16 frames/cardiac cycle. In each frame, left ventricular volume was determined by automatic edge detection employing a quantitative gated SPET program. Additionally, the time-volume curve was fitted by the 4th harmonics of Fourier transform. Ejection fraction (EF, %), peak ejection rate (PER,/sec), peak filling rate (PFR,/sec) and mean filling rate during the initial one-third of diastolic time (1/3 FRm) were calculated from the fitted curve. These parameters were also calculated with planar GBP data. Result: Left ventricular ejection and filling parameters were calculated by SPET GBP with the automatic edge detection program for all patient data. Correlation coefficients of EF, PER, PFR and 1/3 FRm between SPET and planar GBP were 0.91 (p < 0.001), 0.82 (p < 0.001), 0.78 (p < 0.001) and 0.74 (p < 0.001), respectively. Conclusion: Ejection and filling rates can be calculated using SPET GBP with the edge-detection software. These parameters displayed significant correlations with those values obtained via planar GBP. Additional studies are warranted to determine the reliability of parameters with SPET GBP.

Original languageEnglish
Pages (from-to)507-511
Number of pages5
JournalAnnals of nuclear medicine
Volume18
Issue number6
DOIs
Publication statusPublished - Sep 2004
Externally publishedYes

Fingerprint

Photons
Electrocardiography
Gamma Cameras
Tomography
Gated Blood-Pool Imaging
Fourier Analysis
Software

Keywords

  • Blood pool scintigraphy
  • Ejection fraction
  • Ejection rate
  • Filling rate
  • Gated SPET

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Left ventricular ejection and filling rate measurement based on the automatic edge detection method of ECG-gated blood pool single-photon emission tomography. / Higuchi, Takahiro; Taki, Junichi; Nakajima, Kenichi; Kinuya, Seigo; Ikeda, Masatoshi; Namura, Masanobu; Tonami, Norihisa.

In: Annals of nuclear medicine, Vol. 18, No. 6, 09.2004, p. 507-511.

Research output: Contribution to journalArticle

Higuchi, Takahiro ; Taki, Junichi ; Nakajima, Kenichi ; Kinuya, Seigo ; Ikeda, Masatoshi ; Namura, Masanobu ; Tonami, Norihisa. / Left ventricular ejection and filling rate measurement based on the automatic edge detection method of ECG-gated blood pool single-photon emission tomography. In: Annals of nuclear medicine. 2004 ; Vol. 18, No. 6. pp. 507-511.
@article{16a4ab9f11c8401da15a7d28d8d03c85,
title = "Left ventricular ejection and filling rate measurement based on the automatic edge detection method of ECG-gated blood pool single-photon emission tomography",
abstract = "The objective of the present investigation was to determine the feasibility of assessing left ventricular systolic ejection and diastolic filling via the automatic edge detection method employing ECG-gated blood pool single-photon emission tomography (SPET GBP) data. Methods: Thirty-five patients, who had undergone both SPET GBP and ECG-gated equilibrium blood pool scintigraphy by the planar method (planar GBP), were enrolled in this study. Planar GBP was performed with a single-headed gamma camera. From the left anterior oblique projection, data were acquired at 24 frames/cardiac cycle with ECG-gating during the equilibrium state. SPET GBP was conducted utilizing a triple-headed gamma camera, with 60 projection views over 360 degrees by 60 sec per view, in 16 frames/cardiac cycle. In each frame, left ventricular volume was determined by automatic edge detection employing a quantitative gated SPET program. Additionally, the time-volume curve was fitted by the 4th harmonics of Fourier transform. Ejection fraction (EF, {\%}), peak ejection rate (PER,/sec), peak filling rate (PFR,/sec) and mean filling rate during the initial one-third of diastolic time (1/3 FRm) were calculated from the fitted curve. These parameters were also calculated with planar GBP data. Result: Left ventricular ejection and filling parameters were calculated by SPET GBP with the automatic edge detection program for all patient data. Correlation coefficients of EF, PER, PFR and 1/3 FRm between SPET and planar GBP were 0.91 (p < 0.001), 0.82 (p < 0.001), 0.78 (p < 0.001) and 0.74 (p < 0.001), respectively. Conclusion: Ejection and filling rates can be calculated using SPET GBP with the edge-detection software. These parameters displayed significant correlations with those values obtained via planar GBP. Additional studies are warranted to determine the reliability of parameters with SPET GBP.",
keywords = "Blood pool scintigraphy, Ejection fraction, Ejection rate, Filling rate, Gated SPET",
author = "Takahiro Higuchi and Junichi Taki and Kenichi Nakajima and Seigo Kinuya and Masatoshi Ikeda and Masanobu Namura and Norihisa Tonami",
year = "2004",
month = "9",
doi = "10.1007/BF02984568",
language = "English",
volume = "18",
pages = "507--511",
journal = "Annals of Nuclear Medicine",
issn = "0914-7187",
publisher = "Springer Japan",
number = "6",

}

TY - JOUR

T1 - Left ventricular ejection and filling rate measurement based on the automatic edge detection method of ECG-gated blood pool single-photon emission tomography

AU - Higuchi, Takahiro

AU - Taki, Junichi

AU - Nakajima, Kenichi

AU - Kinuya, Seigo

AU - Ikeda, Masatoshi

AU - Namura, Masanobu

AU - Tonami, Norihisa

PY - 2004/9

Y1 - 2004/9

N2 - The objective of the present investigation was to determine the feasibility of assessing left ventricular systolic ejection and diastolic filling via the automatic edge detection method employing ECG-gated blood pool single-photon emission tomography (SPET GBP) data. Methods: Thirty-five patients, who had undergone both SPET GBP and ECG-gated equilibrium blood pool scintigraphy by the planar method (planar GBP), were enrolled in this study. Planar GBP was performed with a single-headed gamma camera. From the left anterior oblique projection, data were acquired at 24 frames/cardiac cycle with ECG-gating during the equilibrium state. SPET GBP was conducted utilizing a triple-headed gamma camera, with 60 projection views over 360 degrees by 60 sec per view, in 16 frames/cardiac cycle. In each frame, left ventricular volume was determined by automatic edge detection employing a quantitative gated SPET program. Additionally, the time-volume curve was fitted by the 4th harmonics of Fourier transform. Ejection fraction (EF, %), peak ejection rate (PER,/sec), peak filling rate (PFR,/sec) and mean filling rate during the initial one-third of diastolic time (1/3 FRm) were calculated from the fitted curve. These parameters were also calculated with planar GBP data. Result: Left ventricular ejection and filling parameters were calculated by SPET GBP with the automatic edge detection program for all patient data. Correlation coefficients of EF, PER, PFR and 1/3 FRm between SPET and planar GBP were 0.91 (p < 0.001), 0.82 (p < 0.001), 0.78 (p < 0.001) and 0.74 (p < 0.001), respectively. Conclusion: Ejection and filling rates can be calculated using SPET GBP with the edge-detection software. These parameters displayed significant correlations with those values obtained via planar GBP. Additional studies are warranted to determine the reliability of parameters with SPET GBP.

AB - The objective of the present investigation was to determine the feasibility of assessing left ventricular systolic ejection and diastolic filling via the automatic edge detection method employing ECG-gated blood pool single-photon emission tomography (SPET GBP) data. Methods: Thirty-five patients, who had undergone both SPET GBP and ECG-gated equilibrium blood pool scintigraphy by the planar method (planar GBP), were enrolled in this study. Planar GBP was performed with a single-headed gamma camera. From the left anterior oblique projection, data were acquired at 24 frames/cardiac cycle with ECG-gating during the equilibrium state. SPET GBP was conducted utilizing a triple-headed gamma camera, with 60 projection views over 360 degrees by 60 sec per view, in 16 frames/cardiac cycle. In each frame, left ventricular volume was determined by automatic edge detection employing a quantitative gated SPET program. Additionally, the time-volume curve was fitted by the 4th harmonics of Fourier transform. Ejection fraction (EF, %), peak ejection rate (PER,/sec), peak filling rate (PFR,/sec) and mean filling rate during the initial one-third of diastolic time (1/3 FRm) were calculated from the fitted curve. These parameters were also calculated with planar GBP data. Result: Left ventricular ejection and filling parameters were calculated by SPET GBP with the automatic edge detection program for all patient data. Correlation coefficients of EF, PER, PFR and 1/3 FRm between SPET and planar GBP were 0.91 (p < 0.001), 0.82 (p < 0.001), 0.78 (p < 0.001) and 0.74 (p < 0.001), respectively. Conclusion: Ejection and filling rates can be calculated using SPET GBP with the edge-detection software. These parameters displayed significant correlations with those values obtained via planar GBP. Additional studies are warranted to determine the reliability of parameters with SPET GBP.

KW - Blood pool scintigraphy

KW - Ejection fraction

KW - Ejection rate

KW - Filling rate

KW - Gated SPET

UR - http://www.scopus.com/inward/record.url?scp=6944230709&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=6944230709&partnerID=8YFLogxK

U2 - 10.1007/BF02984568

DO - 10.1007/BF02984568

M3 - Article

C2 - 15515751

AN - SCOPUS:6944230709

VL - 18

SP - 507

EP - 511

JO - Annals of Nuclear Medicine

JF - Annals of Nuclear Medicine

SN - 0914-7187

IS - 6

ER -